Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | USP8 | P40818 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134048 | 1.00 | TSHR (0.46) | TSHRIDO1RAB9ANPC1AGXT | |
| SCHEMBL5958151 | 0.83 | TSHR (0.43) | TSHRIDO1RAB9ANPC1AGXT | |
| SCHEMBL5958155 | 0.83 | TSHR (0.43) | TSHRIDO1RAB9ANPC1AGXT | |
| SCHEMBL17986336 | 0.81 | AGXT (0.48) | IDO1RAB9ANPC1AGXTSMN1; SMN2 | |
| SCHEMBL17986337 | 0.81 | AGXT (0.48) | IDO1RAB9ANPC1AGXTSMN1; SMN2 | |
| SCHEMBL17986253 | 0.79 | IDO1 (0.47) | IDO1RAB9ANPC1AGXTSMN1; SMN2 | |
| SCHEMBL17986270 | 0.79 | IDO1 (0.53) | TSHRIDO1AGXTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17986271 | 0.79 | IDO1 (0.53) | TSHRIDO1AGXTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17986275 | 0.79 | IDO1 (0.47) | IDO1AGXTALDH1A1L3MBTL1MAOB | |
| SCHEMBL17986276 | 0.79 | IDO1 (0.47) | IDO1AGXTALDH1A1L3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700655-B2 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2010-04-20 | — | — | US | claimed |
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-04-23 | — | — | US | claimed |
| US-20080311074-A1 | Inhibitors against activation of NF-kappaB | INSTITUTE OF MEDICAL MOLECULAR DESIGN INC. (JP) | 2008-12-18 | — | — | US | claimed |
| US-20080234233-A1 | MEDICAMENT FOR TREATMENT OF NEURODEGENERATIVE DISEASES | INSTITUTE OF MEDICINAL MOLECULAR DESIGN INC. (JP) | 2008-09-25 | — | — | US | claimed |
| US-20080090779-A1 | ANTIALLERGIC AGENTS | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2008-04-17 | — | — | US | claimed |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-12-06 | — | — | US | claimed |
| US-20070185059-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | claimed |
| US-20070185110-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | claimed |
| US-20070042997-A1 | Medicament for treatment of dermal pigmentation | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-02-22 | — | — | US | claimed |
| EP-1718653-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | Ligand Pharmaceuticals Inc. (US) | 2006-11-08 | — | — | EP | claimed |
| EP-1649852-A1 | CHROMATOSIS REMEDIES | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-04-26 | — | — | EP | claimed |
| WO-2005082909-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2005-09-09 | — | — | WO | claimed |
| US-4913722-A | HERBICIDES | ICI AMERICAS INC. (US) | 1990-04-03 | — | — | US | claimed |
| US-4877880-A | REACTING AN N-3-SUBSTITUTED ALLYL ANILINE WITH AN ARYLISOTHIOCYANATE, REACTING THE RESULTANT THIOUREA WITH A (TRIFLUORO-)METHANESULFONIC ACID | ICI AMERICAS INC. (US) | 1989-10-31 | — | — | US | claimed |
| EP-0318253-A1 | Iminophenylthiazolidines, process of preparation, and method of use | ICI AMERICAS INC. (US) | 1989-05-31 | — | — | EP | claimed |
| US-20240065267-A1 | PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2024-02-29 | — | — | US | disclosed |
| US-11805779-B2 | Plant disease control composition and method for controlling plant disease by applying the same | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2023-11-07 | — | — | US | disclosed |
| US-4877880-A | REACTING AN N-3-SUBSTITUTED ALLYL ANILINE WITH AN ARYLISOTHIOCYANATE, REACTING THE RESULTANT THIOUREA WITH A (TRIFLUORO-)METHANESULFONIC ACID | ICI AMERICAS INC. (US) | 1989-10-31 | — | — | US | disclosed |
| EP-0318253-A1 | Iminophenylthiazolidines, process of preparation, and method of use | ICI AMERICAS INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| EP-0318253-A1 | Iminophenylthiazolidines, process of preparation, and method of use | ICI AMERICAS INC. (US) | 1989-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240065267-A1 | PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME | SNX1, HAX1, BROX | TSHR 2603/4885IDO1 1188/4885RAB9A 174/4885 |
| US-20080311074-A1 | Inhibitors against activation of NF-kappaB | NFKBIA, IKBKB, RELA | TSHR 4395/4885IDO1 3169/4885RAB9A 3691/4885 |
| US-20080090779-A1 | ANTIALLERGIC AGENTS | NAT1, EPX, HRH2 | TSHR 3122/4885IDO1 91/4885RAB9A 2827/4885 |
| US-20080234233-A1 | MEDICAMENT FOR TREATMENT OF NEURODEGENERATIVE DISEASES | MAPT, TFEB, MAOA | TSHR 4091/4885IDO1 3097/4885RAB9A 3333/4885 |
| US-11805779-B2 | Plant disease control composition and method for controlling plant disease by applying the same | SNX1, HAX1, BROX | TSHR 2603/4885IDO1 1188/4885RAB9A 174/4885 |
| US-20070185110-A1 | Antiallergic agents | NAT1, EPX, AHR | TSHR 2963/4885IDO1 72/4885RAB9A 2704/4885 |
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | NR3C1, NR3C2, MC2R | TSHR 244/4885IDO1 3384/4885RAB9A 3084/4885 |
| US-20070185059-A1 | Antiallergic agents | NAT1, EPX, AHR | TSHR 3004/4885IDO1 80/4885RAB9A 2770/4885 |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | NR3C1, NR3C2, MC2R | TSHR 244/4885IDO1 3384/4885RAB9A 3084/4885 |
| US-20070042997-A1 | Medicament for treatment of dermal pigmentation | TYR, XDH, XPA | TSHR 3558/4885IDO1 569/4885RAB9A 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.