SCHEMBL134123

SCHEMBL134123

N[C@@H](CCC(=O)OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)[O-].N[C@@H](CCC(=O)OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)[O-].[Na+].[Na+]

nearest known ligand 0.35

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 7/20 0.35
CA1 known ✓ P00915 6/20 0.35
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
F2 P00734 2/20 0.32
PRSS1 P07477 2/20 0.32
PRSS2 P07478 2/20 0.32
PRSS3 P35030 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3849732 0.86 GSR (0.39) CA2CA1MMP1MMP2MMP9
SCHEMBL28269564 0.85 CA2 (0.33) CA2CA1MMP1MMP2MMP9
SCHEMBL27662289 0.85 SLC1A1 (0.38) CA2CA1MMP1MMP2MMP9
SCHEMBL339808 0.82 CA2 (0.35) CA2CA1MMP1MMP2MMP9
Potassium Ion SCHEMBL29412573 0.79 CA1 (0.35) CA2CA1MMP1MMP2MMP9
SCHEMBL28475205 0.76
SCHEMBL3849734 0.76 GRM8 (0.39) CA2CA1MMP1MMP2MMP9
D-Glutamate SCHEMBL29412572 0.76 CA2 (0.36) CA2CA1MMP1MMP2MMP9
SCHEMBL29033372 0.75 F2 (0.42) CA2CA1MMP1MMP2MMP9
Potassium Ion SCHEMBL28643240 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4268021-B1 IMAGE FORMING APPARATUS RICOH CO LTD (JP) 2025-08-27 EP disclosed
US-20240012353-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2024-01-11 US disclosed
EP-4268021-A1 IMAGE FORMING APPARATUS Ricoh Company, Ltd. (JP) 2023-11-01 EP disclosed
CN-116670596-A Image forming apparatus 株式会社理光 2023-08-29 CN disclosed
WO-2022138802-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2022-06-30 WO disclosed
EP-2972590-B1 TONER, IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND DEVELOPER RICOH CO LTD (JP) 2020-07-15 EP disclosed
US-20200174388-A1 TWO-COMPONENT DEVELOPER FOR ELECTROSTATIC CHARGE IMAGE DEVELOPMENT Konica Minolta, Inc. (JP) 2020-06-04 US disclosed
CN-105319908-B Image forming apparatus and cartridge processing 株式会社理光 2019-11-08 CN disclosed
CN-104769505-B Toner, developer, and image forming apparatus 株式会社理光 2019-07-12 CN disclosed
CN-104995566-B Toner, developer, and image forming apparatus 株式会社理光 2019-06-21 CN disclosed
US-20040136763-A1 Cleaning unit, process cartridge, image forming apparatus, and toner RICOH COMPANY, LTD. (JP) 2004-07-15 US disclosed
EP-1431843-A2 Cleanerless image forming apparatus and process cartridge for use in the same Ricoh Company, Ltd. (JP) 2004-06-23 EP disclosed
EP-1426828-A2 Dry toner and process cartridge, image forming process and apparatus using the same Ricoh Company, Ltd. (JP) 2004-06-09 EP disclosed
EP-1413933-A2 cleaning unit with a cleaning blade for an image forming apparatus Ricoh Company, Ltd. (JP) 2004-04-28 EP disclosed
US-20040067189-A1 External additive for toner for electrophotography, toner for electrophotography, double-component developer for electrophotography, image-forming process using the toner, and image-forming apparatus using the toner RICOH COMPANY, LTD. (JP) 2004-04-08 US disclosed
EP-1403742-A2 Cleaning unit having two cleaning blades Ricoh Company, Ltd. (JP) 2004-03-31 EP disclosed
EP-1383010-A1 External additive for toner for electrophotography, toner for electrophotography, double-component developer for electrophotography, image forming process using the toner, and image-forming apparatus using the toner Ricoh Company, Ltd. (JP) 2004-01-21 EP disclosed
US-20030219669-A1 Toner for electrophotography, developer using the same, image-forming process cartridge using the same, image-forming apparatus using the same and image-forming process using the same RICOH COMPANY, LTD. (JP) 2003-11-27 US disclosed
EP-1347341-A2 Toner for electrophotography, developer, image-forming process cartridge, image-forming apparatus and image-forming process using the same Ricoh Company, Ltd. (JP) 2003-09-24 EP disclosed
US-6329115-B1 IMAGE TRANSFER RATIO IS HIGH AND CLEAR TONER IMAGE CAN BE FORMED, FREE FROM ODOR AND SHOWS EXCELLENT PRESERVATION STABILITY WITH NO BLOCKING, PARTICLE CONTAINING A RESIN, A COLORANT, A FLUIDITY-IMPARTING AGENT AND A VOLATILE ORGANIC RICOH COMPANY, LTD. (JP) 2001-12-11 US disclosed