SCHEMBL339808

SCHEMBL339808

N[C@@H](CCC(=O)[O-])C(=O)OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.N[C@@H](CCC(=O)[O-])C(=O)OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[Na+].[Na+]

nearest known ligand 0.35

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 9/20 0.35
CA1 known ✓ P00915 9/20 0.35
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
F2 P00734 2/20 0.32
PRSS1 P07477 2/20 0.32
PRSS2 P07478 2/20 0.32
PRSS3 P35030 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL29412573 0.97 CA1 (0.35) CA2CA1MMP1MMP2MMP9
SCHEMBL3849734 0.86 GRM8 (0.39) CA2CA1MMP1MMP2MMP9
SCHEMBL28269564 0.85 CA2 (0.33) CA2CA1MMP1MMP2MMP9
SCHEMBL134123 0.82 CA2 (0.35) CA2CA1MMP1MMP2MMP9
D-Glutamate SCHEMBL29412572 0.76 CA2 (0.36) CA2CA1MMP1MMP2MMP9
SCHEMBL3849732 0.76 GSR (0.39) CA2CA1MMP1MMP2MMP9
SCHEMBL27662289 0.75 SLC1A1 (0.38) CA2CA1MMP1MMP2MMP9
D-Glutamate SCHEMBL28482838 0.71 CA2 (0.40) CA2CA1MMP1MMP2MMP9
SCHEMBL29033372 0.69 F2 (0.42) CA2CA1MMP1MMP2MMP9
SCHEMBL27809184 0.68 CA2 (0.44) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116670596-A Image forming apparatus 株式会社理光 2023-08-29 CN disclosed
US-20200174388-A1 TWO-COMPONENT DEVELOPER FOR ELECTROSTATIC CHARGE IMAGE DEVELOPMENT Konica Minolta, Inc. (JP) 2020-06-04 US disclosed
US-10303071-B2 Toner, developer, image forming apparatus, and process cartridge RICHOH COMPANY, LTD. (JP) 2019-05-28 US disclosed
US-20180253022-A1 TONER, DEVELOPER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2018-09-06 US disclosed
EP-1347341-B2 Use of a toner and developer for electrophotography, image-forming process cartridge, image-forming apparatus and image-forming process using the toner RICOH CO LTD (JP) 2018-01-10 EP disclosed
US-20170248896-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2017-08-31 US disclosed
EP-3195064-A1 IMAGE FORMING APPARATUS Ricoh Company, Ltd. (JP) 2017-07-26 EP disclosed
US-9625848-B2 Toner and method for producing toner RICOH COMPANY, LTD. (JP) 2017-04-18 US disclosed
US-8948677-B2 Protective agent block, method of manufacturing the same, process cartridge, and image forming apparatus RICOH COMPANY, LTD. (JP) 2015-02-03 US disclosed
US-8871417-B2 Toner, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-10-28 US disclosed
US-20050002705-A1 Cleaning device, process cartridge, image forming apparatus and toner RICOH COMPANY, LTD. (JP) 2005-01-06 US disclosed
US-20040175641-A1 Toner, developer using the same, toner container using the same, process cartridge using the same, image-forming process using the same and image-forming apparatus using the same RICOH COMPANY, LTD. (JP) 2004-09-09 US disclosed
US-20040146795-A1 Toner and image forming apparatus using the toner RICOH COMPANY, LTD. (JP) 2004-07-29 US disclosed
US-20040142265-A1 Dry toner, and process cartridge, image forming process and apparatus using the same RICOH COMPANY, LTD. (JP) 2004-07-22 US disclosed
US-20040137356-A1 Image forming process and image forming apparatus RICOH COMPANY, LTD. (JP) 2004-07-15 US disclosed
EP-1426828-A2 Dry toner and process cartridge, image forming process and apparatus using the same Ricoh Company, Ltd. (JP) 2004-06-09 EP disclosed
US-20040067189-A1 External additive for toner for electrophotography, toner for electrophotography, double-component developer for electrophotography, image-forming process using the toner, and image-forming apparatus using the toner RICOH COMPANY, LTD. (JP) 2004-04-08 US disclosed
EP-1383010-A1 External additive for toner for electrophotography, toner for electrophotography, double-component developer for electrophotography, image forming process using the toner, and image-forming apparatus using the toner Ricoh Company, Ltd. (JP) 2004-01-21 EP disclosed
US-20030219669-A1 Toner for electrophotography, developer using the same, image-forming process cartridge using the same, image-forming apparatus using the same and image-forming process using the same RICOH COMPANY, LTD. (JP) 2003-11-27 US disclosed
EP-1347341-A2 Toner for electrophotography, developer, image-forming process cartridge, image-forming apparatus and image-forming process using the same Ricoh Company, Ltd. (JP) 2003-09-24 EP disclosed