Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21398140 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTALDH1A1HPGDLIMK1 | |
| SCHEMBL72743 | 0.80 | MAOA (0.49) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL25662762 | 0.77 | CYP1A2 (0.35) | MAPTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL13509566 | 0.77 | L3MBTL1 (0.46) | SMN1; SMN2MAPTALDH1A1HPGDMCL1 | |
| SCHEMBL30356598 | 0.76 | CYP1A2 (0.42) | SMN1; SMN2MAPTALDH1A1HPGDLIMK1 | |
| SCHEMBL22483141 | 0.76 | CYP1A2 (0.42) | SMN1; SMN2MAPTALDH1A1HPGDLIMK1 | |
| SCHEMBL25662760 | 0.75 | MCL1 (0.38) | SMN1; SMN2MAPTALDH1A1HPGDMCL1 | |
| SCHEMBL483929 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTALDH1A1HPGDLIMK1 | |
| SCHEMBL19039382 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPTALDH1A1HPGDLIMK1 | |
| SCHEMBL13509565 | 0.73 | TDO2 (0.40) | MCL1CYP17A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172057-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| US-10040794-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2018-08-07 | — | — | US | disclosed |
| US-20170186977-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2017-06-29 | — | — | US | disclosed |
| US-9314468-B2 | Chemokine receptor modulators | ALTIRIS THERAPEUTICS, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20130172330-A1 | Chemokine Receptor Modulators | ALTIRIS THERAPEUTICS, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8338448-B2 | Chemokine receptor modulators | ALTIRIS THERAPEUTICS, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100029634-A1 | Chemokine Receptor Modulators | ALTIRIS THERAPEUTICS, INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172057-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE | CHRM1, CHRM2, CHRM4 | SMN1; SMN2 3262/4885MAPT 4606/4885ALDH1A1 3072/4885 |
| US-20130172330-A1 | Chemokine Receptor Modulators | CCR5, CXCR4, ACKR3 | SMN1; SMN2 4379/4885MAPT 1019/4885ALDH1A1 2030/4885 |
| US-10040794-B2 | Condensed cyclic compound and organic light-emitting device including the same | CRY1, CCNE2, CRY2 | SMN1; SMN2 4546/4885MAPT 1482/4885ALDH1A1 352/4885 |
| US-20170186977-A1 | Organic Electroluminescent Materials and Devices | KYNU, EML4, INMT | SMN1; SMN2 4719/4885MAPT 549/4885ALDH1A1 1063/4885 |
| US-20100029634-A1 | Chemokine Receptor Modulators | CCR5, CXCR4, ACKR3 | SMN1; SMN2 4379/4885MAPT 1019/4885ALDH1A1 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.