Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17212019 | 0.83 | MEN1 (0.41) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL379262 | 0.83 | MEN1 (0.50) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL9748657 | 0.81 | MMP8 (0.44) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL1313060 | 0.81 | CYP4F2 (0.47) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL18541186 | 0.79 | CYP4F2 (0.50) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL1315228 | 0.79 | CYP4F2 (0.50) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL13780513 | 0.79 | MEN1 (0.39) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL31265512 | 0.78 | PKM (0.38) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL27861619 | 0.78 | MEN1 (0.46) | MEN1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL1026954 | 0.78 | MEN1 (0.46) | MEN1KMT2AALDH1A1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470514-B1 | PSEUDO-DIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-07-12 | — | — | EP | disclosed |
| US-20120309674-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT (FR) | 2012-12-06 | — | — | US | disclosed |
| US-20120309674-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT (FR) | 2012-12-06 | — | — | US | disclosed |
| US-7618999-B2 | Process of obtaining taxosteroids and precursors thereof | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2009-11-17 | — | — | US | disclosed |
| US-7618999-B2 | Process of obtaining taxosteroids and precursors thereof | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2009-11-17 | — | — | US | disclosed |
| US-20070185108-A1 | PROCESS OF OBTAINING TAXOSTEROIDS AND PRECURSORS THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2007-08-09 | — | — | US | disclosed |
| US-20070185108-A1 | PROCESS OF OBTAINING TAXOSTEROIDS AND PRECURSORS THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309674-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | MMP3, MMP11, TIMP3 | MEN1 1234/4885KMT2A 3532/4885ALDH1A1 2288/4885 |
| US-20070185108-A1 | PROCESS OF OBTAINING TAXOSTEROIDS AND PRECURSORS THEREOF | CYP11B1, CYP11B2, HSD3B2 | MEN1 2734/4885KMT2A 4065/4885ALDH1A1 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.