Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628538 | 0.88 | ASIC3 (0.33) | ASIC3AOC3LNPEPNUDT1HRH4 | |
| SCHEMBL13628956 | 0.84 | CYP2D6 (0.37) | AOC3ADRA2AADRA2BADRA2C | |
| SCHEMBL13628514 | 0.76 | HTR7 (0.39) | HRH4NR3C2 | |
| SCHEMBL13628668 | 0.73 | HRH3 (0.36) | HRH4 | |
| SCHEMBL13628513 | 0.71 | CYP2D6 (0.39) | ADRA2AADRA2BADRA2C | |
| SCHEMBL13628670 | 0.64 | CYP1A2 (0.46) | — | |
| SCHEMBL13628672 | 0.64 | CYP2D6 (0.55) | — | |
| SCHEMBL13628669 | 0.64 | CYP2D6 (0.39) | ASIC3NR3C2 | |
| SCHEMBL25453079 | 0.63 | EGFR (0.48) | ASIC3 | |
| SCHEMBL13658798 | 0.63 | HRH3 (0.62) | ASIC3HRH4ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |