Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920933 | 0.79 | PTGS2 (0.54) | PTGS2TBXA2RCCR2 | |
| SCHEMBL13628832 | 0.77 | TRPC5 (0.38) | PTGS2RAB9A | |
| SCHEMBL13628859 | 0.76 | PTGS2 (0.45) | PTGS2TBXA2R | |
| SCHEMBL13628853 | 0.76 | PTGS2 (0.37) | PTGS2TBXA2R | |
| SCHEMBL13628852 | 0.76 | PDE1A (0.39) | PTGS2CCR2 | |
| SCHEMBL13628857 | 0.75 | CCR2 (0.40) | PTGS2TBXA2RCCR2 | |
| SCHEMBL13628824 | 0.75 | RAB9A (0.36) | PTGS2RAB9ATBXA2R | |
| SCHEMBL13628847 | 0.73 | CYP11B2 (0.43) | PTGS2 | |
| SCHEMBL13628850 | 0.73 | PTGS2 (0.36) | PTGS2RAB9ATBXA2R | |
| SCHEMBL13628839 | 0.73 | PDE2A (0.34) | PTGS2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612070-B2 | Heterocyclic compounds as antiinflammatory agents and cyclooxygenase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-11-03 | — | — | US | disclosed |