Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680830 | 0.89 | RARA (0.44) | SMN1; SMN2PDE10ARARARARBALDH1A1 | |
| SCHEMBL13680835 | 0.87 | MAP4K4 (0.42) | SCN9A | |
| SCHEMBL13680836 | 0.87 | NPC1 (0.44) | MAPTSMN1; SMN2ADORA3TRPV3ATR | |
| SCHEMBL13680837 | 0.87 | ALDH1A1 (0.40) | ATRKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL13680828 | 0.87 | ALDH1A1 (0.42) | MAPTSMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL13680834 | 0.84 | PDE10A (0.39) | MAPTSMN1; SMN2ADORA3PDE10ATRPV3 | |
| SCHEMBL13680827 | 0.82 | KMT2A (0.50) | MAPTSMN1; SMN2PDE10AKMT2AALDH1A1 | |
| SCHEMBL13680840 | 0.82 | RAB9A (0.41) | MAPTSMN1; SMN2SCN9AKMT2AALDH1A1 | |
| SCHEMBL3854280 | 0.82 | MEN1 (0.50) | PDE10ATRPV3KMT2AALDH1A1 | |
| SCHEMBL13680815 | 0.80 | PDE10A (0.46) | MAPTSMN1; SMN2ADORA3PDE10ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |