Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17323452 | 1.00 | TSHR (0.35) | TSHR | |
| SCHEMBL12755415 | 1.00 | TSHR (0.35) | TSHR | |
| SCHEMBL19418710 | 1.00 | TSHR (0.35) | TSHR | |
| SCHEMBL19418712 | 1.00 | TSHR (0.35) | TSHR | |
| SCHEMBL10168385 | 1.00 | TSHR (0.35) | TSHR | |
| SCHEMBL15339367 | 1.00 | TSHR (0.35) | TSHR | |
| SCHEMBL19418714 | 1.00 | TSHR (0.35) | TSHR | |
| SCHEMBL19418717 | 1.00 | TSHR (0.35) | TSHR | |
| SCHEMBL19418719 | 0.89 | CA2 (0.39) | TSHR | |
| SCHEMBL2028884 | 0.89 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926400-B2 | Method of making hydroxyaryl-functionalized interpolymer by free radical initiated polymerization | BRIDGESTONE CORPORATION (JP) | 2018-03-27 | — | — | US | claimed |
| US-8871871-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2014-10-28 | — | — | US | claimed |
| WO-2025038619-A1 | PRODUCING PARACETAMOL FROM BIOMASS-DERIVED P-HYDROXYBENZOIC ACID AND P-HYDROXYBENZAMIDE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-02-20 | — | — | WO | disclosed |
| US-20250059130-A1 | PRODUCING PARACETAMOL FROM BIOMASS-DERIVED P-HYDROXYBENZOIC ACID AND P-HYDROXYBENZAMIDE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-02-20 | — | — | US | disclosed |
| CN-107921144-B | Aureostatin analogs and conjugate conjugates thereof with cell-binding molecules | 杭州多禧生物科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-116726190-A | Aureostatin analogs and conjugate conjugates thereof with cell-binding molecules | 杭州多禧生物科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-11731930-B2 | Processes for preparing a (1,2-dimethyl-3-methylenecyclopentyl)acetate compound and (1,2-dimethyl-3-methylenecyclopentyl)acetaldehyde | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-08-22 | — | — | US | disclosed |
| US-11117987-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2021-09-14 | — | — | US | disclosed |
| US-11028195-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2021-06-08 | — | — | US | disclosed |
| CN-110872438-A | Polyamic acid-imide composition, preparation method thereof and polyimide film | 株式会社东进世美肯 | 2020-03-10 | — | — | CN | disclosed |
| US-20190322777-A1 | Hydroxyaryl Functionalized Polymers | BRIDGESTONE CORPORATION (JP) | 2019-10-24 | — | — | US | disclosed |
| US-20080139802-A1 | Converting 2'-deoxy-2'-fluoro-2'-methyl-D-ribonolactones derivatives to 3-fluoro-3-methyl-2-chlorofuran compounds using chlorinating agent such as sulfuryl chloride, thionyl chloride or phosphorus oxychloride and tetrabutylammonium bromide | PHARMASSET, INC. | 2008-06-12 | — | — | US | disclosed |
| EP-1912974-A1 | IMIDAZOLYL-PYRIMIDINE COMPOUNDS FOR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | AstraZeneca AB (SE) | 2008-04-23 | — | — | EP | disclosed |
| US-20080033184-A1 | INTERMEDIATES AND METHODS FOR SEROTONERGIC AGONIST SYNTHESIS | ALCON MANUFACTURING, LTD. (US) | 2008-02-07 | — | — | US | disclosed |
| EP-1828183-A1 | 4- (4- (IMIDAZOL-4-YL) PYRIMIDIN-2-YLAMINO) BENZAMIDES AS CDK INHIBITORS | AstraZeneca AB (SE) | 2007-09-05 | — | — | EP | disclosed |
| US-20070069177-A1 | Organometallic compounds, processes for the preparation thereof and methods of use thereof | PRAXAIR TECHNOLOGY, INC. | 2007-03-29 | — | — | US | disclosed |
| WO-2007015064-A1 | IMIDAZOLYL-PYRIMIDINE COMPOUNDS FOR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2007-02-08 | — | — | WO | disclosed |
| WO-2006064251-A1 | 4- (4- (IMIDAZOL-4-YL) PYRIMIDIN-2-YLAMINO) BENZAMIDES AS CDK INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |
| US-5986094-A | XANTHENE DYES AND PHTHALEIN DYES FOR FLUORESCEENT DYES | ROCHE DIAGNOSTICS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0086438-A1 | Process and intermediates for preparing 4-hydroxymethyl-1-phthalazone derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1983-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322777-A1 | Hydroxyaryl Functionalized Polymers | HAAO, HCAR3, VCL | TSHR 3633/4885 |
| US-11028195-B2 | Hydroxyaryl functionalized polymers | HAAO, HCAR3, VCL | TSHR 3597/4885 |
| US-20080139802-A1 | Converting 2'-deoxy-2'-fluoro-2'-methyl-D-ribonolactones derivatives to 3-fluoro-3-methyl-2-chlorofuran compounds using chlorinating agent such as sulfuryl chloride, thionyl chloride or phosphorus oxychloride and tetrabutylammonium bromide | FBL, NSUN2, RNGTT | TSHR 1622/4885 |
| US-11731930-B2 | Processes for preparing a (1,2-dimethyl-3-methylenecyclopentyl)acetate compound and (1,2-dimethyl-3-methylenecyclopentyl)acetaldehyde | ADH1C, AKR1C4, AKR1C2 | TSHR 3819/4885 |
| US-20250059130-A1 | PRODUCING PARACETAMOL FROM BIOMASS-DERIVED P-HYDROXYBENZOIC ACID AND P-HYDROXYBENZAMIDE | PAM, HPD, HMBS | TSHR 3767/4885 |
| US-20080033184-A1 | INTERMEDIATES AND METHODS FOR SEROTONERGIC AGONIST SYNTHESIS | HTR3B, HTR3A, HTR4 | TSHR 480/4885 |
| US-11117987-B2 | Hydroxyaryl functionalized polymers | HAAO, HCAR3, VCL | TSHR 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.