SCHEMBL13736736

SCHEMBL13736736

CCOC(=O)c1cc2cccc(C(F)(F)F)c2s1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.60
HDAC4 P56524 2/20 0.60
HDAC1 Q13547 2/20 0.60
HDAC6 Q9UBN7 2/20 0.60
HDAC7 Q8WUI4 1/20 0.60
HDAC2 Q92769 1/20 0.60
HDAC10 Q969S8 1/20 0.60
HDAC11 Q96DB2 1/20 0.60
HDAC8 Q9BY41 1/20 0.60
HDAC9 Q9UKV0 1/20 0.60
HDAC5 Q9UQL6 1/20 0.60
MAPT P10636 3/20 0.55
KDM4E B2RXH2 3/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
NPC1 O15118 2/20 0.55
CASP3 P42574 1/20 0.55
RAB9A P51151 1/20 0.55
ATM Q13315 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2895700 0.85 HDAC3 (0.69) HDAC3HDAC4HDAC1HDAC6HDAC7
SCHEMBL29443049 0.83 KDM4E (0.57) HDAC3HDAC4HDAC1HDAC6MAPT
SCHEMBL15595465 0.83 KDM4E (0.57) HDAC3HDAC4HDAC1HDAC6MAPT
SCHEMBL18264002 0.81 KDM4E (0.60) HDAC3HDAC4HDAC1HDAC6HDAC7
SCHEMBL18264007 0.81 HDAC3 (0.58) HDAC3HDAC4HDAC1HDAC6HDAC7
SCHEMBL1849673 0.81 KDM4E (0.57) HDAC3HDAC4HDAC1HDAC6MAPT
SCHEMBL13737947 0.78 SLC9A1 (0.55) HDAC3HDAC4HDAC1HDAC6MAPT
SCHEMBL2892808 0.78 HDAC6 (0.72) HDAC3HDAC4HDAC1HDAC6HDAC7
SCHEMBL30020347 0.78 KDM4E (0.83) HDAC3HDAC4HDAC1HDAC6MAPT
SCHEMBL19756725 0.77 HDAC6 (0.70) HDAC3HDAC4HDAC1HDAC6HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US claimed
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-08 US claimed
EP-2923574-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP claimed
EP-4570313-A2 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2025-06-18 EP disclosed
EP-4219477-A1 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2023-08-02 EP disclosed
US-10626095-B2 Cyanotriazole compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2020-04-21 US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US disclosed
US-20160229816-A1 CYANOTRIAZOLE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2016-08-11 US disclosed
US-9265251-B2 Agrichemical composition and method of promoting growth of plant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-02-23 US disclosed
US-9215871-B2 Agrichemical composition and method of promoting growth of plant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-22 US disclosed
EP-2923574-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
CN-104902752-A Method for promoting plant growth SUMITOMO CHEMICAL CO 2015-09-09 CN disclosed
US-9119396-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-09-01 US disclosed
US-20140135214-A1 AGRICHEMICAL COMPOSITION AND METHOD OF PROMOTING GROWTH OF PLANT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-05-15 US disclosed
US-20140135213-A1 AGRICHEMICAL COMPOSITION AND METHOD OF PROMOTING GROWTH OF PLANT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-05-15 US disclosed
WO-2014073622-A1 METHOD FOR PROMOTING PLANT GROWTH 住友化学株式会社 (JP) 2014-05-15 WO disclosed
US-20140121113-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-05-01 US disclosed
EP-2706851-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company, Limited (JP) 2014-03-19 EP disclosed
WO-2012153860-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626095-B2 Cyanotriazole compounds CS, PC, ACAT1 HDAC3 127/4885HDAC4 590/4885HDAC1 177/4885
US-20140135213-A1 AGRICHEMICAL COMPOSITION AND METHOD OF PROMOTING GROWTH OF PLANT PIR, CYP51A1, PTN HDAC3 3154/4885HDAC4 4300/4885HDAC1 3745/4885
US-20140135214-A1 AGRICHEMICAL COMPOSITION AND METHOD OF PROMOTING GROWTH OF PLANT DDT, AADAC, THRB HDAC3 2747/4885HDAC4 3821/4885HDAC1 3247/4885
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH BOLA2; BOLA2B, BROX, TET1 HDAC3 1305/4885HDAC4 931/4885HDAC1 516/4885
US-20140121113-A1 METHOD FOR PROMOTING PLANT GROWTH MYB, PRMT1, GFM1 HDAC3 812/4885HDAC4 1168/4885HDAC1 488/4885
US-20160229816-A1 CYANOTRIAZOLE COMPOUNDS CS, PC, ACAT1 HDAC3 127/4885HDAC4 590/4885HDAC1 177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.