Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270149 | 0.79 | KMT2A (0.57) | KMT2AALDH1A1TP53HPGD | |
| SCHEMBL268470 | 0.71 | KMT2A (0.61) | KMT2AALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL8029443 | 0.71 | ALOX5 (0.41) | GNAO1GNAI3GNAI1ALOX5PTGS1 | |
| SCHEMBL19336853 | 0.71 | ADORA2B (0.43) | PTGS1PTGS2MGLLFAAHTSHR | |
| Hydrochloric Acid SCHEMBL27558043 | 0.70 | GNAO1 (0.43) | GNAO1GNAI3GNAI1ALDH1A1CYP1A2 | |
| SCHEMBL3310643 | 0.69 | GNAO1 (0.46) | GNAO1GNAI3GNAI1ALDH1A1CYP1A2 | |
| SCHEMBL8751413 | 0.69 | GNAO1 (0.46) | GNAO1GNAI3GNAI1ALDH1A1CYP1A2 | |
| SCHEMBL3313743 | 0.69 | GNAO1 (0.46) | GNAO1GNAI3GNAI1ALDH1A1CYP1A2 | |
| SCHEMBL8057789 | 0.69 | MAPT (0.53) | KMT2AGNAO1GNAI3GNAI1ALDH1A1 | |
| SCHEMBL25867919 | 0.69 | RGS4 (0.43) | PTGS1PTGS2MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105260-A1 | Molecules to Enhance Percutaneous Delivery and Methods for Discovery Therefor | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2009-04-23 | — | — | US | disclosed |
| US-20090105260-A1 | Molecules to Enhance Percutaneous Delivery and Methods for Discovery Therefor | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105260-A1 | Molecules to Enhance Percutaneous Delivery and Methods for Discovery Therefor | NOTUM, TRPV1, TRPV4 | KMT2A 4845/4885GNAO1 4632/4885GNAI3 4218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.