Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 5/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.32 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389538 | 0.97 | CA4 (0.50) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Water SCHEMBL976875 | 0.94 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL6669346 | 0.94 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Water SCHEMBL1133745 | 0.94 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL8984838 | 0.94 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL15251308 | 0.94 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL865415 | 0.94 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL11344222 | 0.94 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL9656600 | 0.94 | CA4 (0.55) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL6670067 | 0.94 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7416582-B2 | Method and apparatus for NOx and Hg removal | CANSOLV TECHNOLOGIES INC. (CA) | 2008-08-26 | — | — | US | claimed |
| US-20060021506-A1 | Method and apparatus for NOx and Hg removal | CANSOLV TECHNOLOGIES INC. (CA) | 2006-02-02 | — | — | US | claimed |
| WO-2006010262-A1 | METHOD AND APPARATUS FOR NOX AND Hg REMOVAL | CANSOLV TECHNOLOGIES INC. (CA) | 2006-02-02 | — | — | WO | claimed |
| US-7416582-B2 | Method and apparatus for NOx and Hg removal | CANSOLV TECHNOLOGIES INC. (CA) | 2008-08-26 | — | — | US | disclosed |
| US-7384616-B2 | Waste gas treatment process including removal of mercury | CANSOLV TECHNOLOGIES INC. (CA) | 2008-06-10 | — | — | US | disclosed |
| US-20080044333-A1 | Method and apparatus for NOx and Hg removal | HAKKA LEO E | 2008-02-21 | — | — | US | disclosed |
| WO-2006136016-A1 | WASTE GAS TREATMENT PROCESS INCLUDING REMOVAL OF MERCURY | CANSOLV TECHNOLOGIES INC. (CA) | 2006-12-28 | — | — | WO | disclosed |
| US-20060286017-A1 | Waste gas treatment process including removal of mercury | CANSOLV TECHNOLOGIES INC. (CA) | 2006-12-21 | — | — | US | disclosed |
| US-20060021506-A1 | Method and apparatus for NOx and Hg removal | CANSOLV TECHNOLOGIES INC. (CA) | 2006-02-02 | — | — | US | disclosed |
| WO-2006010262-A1 | METHOD AND APPARATUS FOR NOX AND Hg REMOVAL | CANSOLV TECHNOLOGIES INC. (CA) | 2006-02-02 | — | — | WO | disclosed |