SCHEMBL1394685

SCHEMBL1394685

O=C(O)CN(CCN(CCN(CC(=O)O)C(COCc1ccccc1)C(=O)O)CP(=O)(O)O)C(COCc1ccccc1)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.39
SLC1A1 P43005 1/20 0.38
FOLH1 Q04609 2/20 0.37
PPARA Q07869 1/20 0.35
TSHR P16473 1/20 0.35
CA1 P00915 3/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
LAP3 P28838 3/20 0.33
ANPEP P15144 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6428109 1.00 MAOB (0.39) MAOBSLC1A1FOLH1PPARATSHR
SCHEMBL8059292 0.88 MAOB (0.43) MAOBSLC1A1FOLH1PPARATSHR
SCHEMBL8068462 0.88 MAOB (0.43) MAOBSLC1A1FOLH1PPARATSHR
SCHEMBL8068485 0.88 MAOB (0.43) MAOBSLC1A1FOLH1PPARATSHR
SCHEMBL7594884 0.88 SLC1A1 (0.47) MAOBSLC1A1FOLH1PPARATSHR
SCHEMBL4938839 0.87 MAOB (0.42) MAOBSLC1A1FOLH1PPARATSHR
SCHEMBL29406971 0.87 MAOB (0.42) MAOBSLC1A1FOLH1PPARATSHR
SCHEMBL1144138 0.87 MAOB (0.42) MAOBSLC1A1FOLH1PPARATSHR
SCHEMBL6428029 0.84 LAP3 (0.43) LAP3ANPEP
SCHEMBL8059372 0.84 SLC1A1 (0.44) MAOBSLC1A1FOLH1PPARATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7780952-B2 Distinguish between tumor cells and normal cells using novel contrast agents that contain a Magnetic Resonance Imaging (MRI) detectable moiety bound, optionally through a spacer, to a (pseudo)nutrient such as glucose, a natural or unnatural amino acid such as agmatine, or a polyamine such as spermidine BRACCO IMAGING SPA (IT) 2010-08-24 US claimed
EP-1509254-B1 NEW AGENTS FOR MAGNETIC IMAGING METHOD BRACCO IMAGING SPA (IT) 2009-01-14 EP claimed
US-20050175543-A1 Distinguish between tumor cells and normal cells using novel contrast agents that contain a Magnetic Resonance Imaging (MRI) detectable moiety bound, optionally through a spacer, to a (pseudo)nutrient such as glucose, a natural or unnatural amino acid such as agmatine, or a polyamine such as spermidine BRACCO IMAGING S.P.A. (IT) 2005-08-11 US claimed
EP-1369134-A1 New agents for magnetic imaging method Bracco Imaging S.p.A. (IT) 2003-12-10 EP claimed
US-9402924-B2 Diagnostic compounds for targeting a chemokine receptors GUERBET (FR) 2016-08-02 US disclosed
US-8926945-B2 Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium GUERBET (FR) 2015-01-06 US disclosed
US-20120009124-A1 USE OF BUFFERS FOR RADIONUCLIDE COMPLEXATION GUERBET (FR) 2012-01-12 US disclosed
US-20110092806-A1 Compounds Comprising a Biological Target Recognizing Part, Coupled to a Signal Part Capable of Complexing Gallium GUEREBET (FR) 2011-04-21 US disclosed
EP-1635878-B1 PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING OF MATRIX METALLOPROTEINASES GUERBET SA (FR) 2010-12-29 EP disclosed
US-7780952-B2 Distinguish between tumor cells and normal cells using novel contrast agents that contain a Magnetic Resonance Imaging (MRI) detectable moiety bound, optionally through a spacer, to a (pseudo)nutrient such as glucose, a natural or unnatural amino acid such as agmatine, or a polyamine such as spermidine BRACCO IMAGING SPA (IT) 2010-08-24 US disclosed
EP-1509254-B1 NEW AGENTS FOR MAGNETIC IMAGING METHOD BRACCO IMAGING SPA (IT) 2009-01-14 EP disclosed
US-20060239913-A1 Peptide conjugate for magnetic resonance imaging GUERBET (FR) 2006-10-26 US disclosed
EP-1635878-A2 PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING GUERBET (FR) 2006-03-22 EP disclosed
US-20050175543-A1 Distinguish between tumor cells and normal cells using novel contrast agents that contain a Magnetic Resonance Imaging (MRI) detectable moiety bound, optionally through a spacer, to a (pseudo)nutrient such as glucose, a natural or unnatural amino acid such as agmatine, or a polyamine such as spermidine BRACCO IMAGING S.P.A. (IT) 2005-08-11 US disclosed
WO-2004112840-A2 PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING GUERBET (FR) 2004-12-29 WO disclosed
EP-1369134-A1 New agents for magnetic imaging method Bracco Imaging S.p.A. (IT) 2003-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110092806-A1 Compounds Comprising a Biological Target Recognizing Part, Coupled to a Signal Part Capable of Complexing Gallium KLK3, IGF1R, GIPR MAOB 3268/4885SLC1A1 3542/4885FOLH1 118/4885
US-20120009124-A1 USE OF BUFFERS FOR RADIONUCLIDE COMPLEXATION CA5B, CA3, CA1 MAOB 1720/4885SLC1A1 795/4885FOLH1 17/4885
US-20060239913-A1 Peptide conjugate for magnetic resonance imaging MMP11, MMP26, MMP3 MAOB 1655/4885SLC1A1 1365/4885FOLH1 87/4885
US-20050175543-A1 Distinguish between tumor cells and normal cells using novel contrast agents that contain a Magnetic Resonance Imaging (MRI) detectable moiety bound, optionally through a spacer, to a (pseudo)nutrient such as glucose, a natural or unnatural amino acid such as agmatine, or a polyamine such as spermidine SLC7A5, SLC2A9, SLC2A1 MAOB 4475/4885SLC1A1 34/4885FOLH1 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.