SCHEMBL13958013

SCHEMBL13958013

C=Cc1ccc(CN(CC(=O)O)c2ccc(O)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
ESRRG P62508 3/20 0.39
CA2 P00918 1/20 0.39
CAMK2A Q9UQM7 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
NR3C1 P04150 1/20 0.38
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
HSP90AA1 P07900 1/20 0.37
GAA P10253 1/20 0.37
MTOR P42345 1/20 0.37
G6PC1 P35575 1/20 0.36
KDM4E B2RXH2 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13958502 0.88 NR3C1 (0.43) ESR1NR3C1ALDH1A1MAPTKMT2A
SCHEMBL7627812 0.83 ALDH1A1 (0.42) ESRRGALDH1A1MAPTGAAKDM4E
SCHEMBL515232 0.78 ALDH1A1 (0.41) CA2ALDH1A1KDM4EALOX15TSHR
SCHEMBL6389774 0.78 ALDH1A1 (0.48) ESR1ESR2NR3C1ALDH1A1MAPT
SCHEMBL5811429 0.77 RAB9A (0.50) ESR1ESR2ESRRGNR3C1MEN1
SCHEMBL12545554 0.77 MEP1B (0.42) CA2ALDH1A1KDM4EALOX15TSHR
SCHEMBL6560450 0.76 CRHBP (0.47) ALDH1A1MAPTKMT2AGAACYP3A4
SCHEMBL13645018 0.76 CA2 (0.46) ESR1ESR2ESRRGCA2CAMK2A
SCHEMBL13958014 0.74 LTA4H (0.44) MAOAMAOBMEN1KMT2AKDM4E
SCHEMBL13958501 0.74 AGTR2 (0.38) ALDH1A1TSHRAGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1834802-B1 Infrared-sensitive lithographic printing plate FUJIFILM CORP (JP) 2009-01-14 EP disclosed
US-7306893-B2 Intermediate layer contains a unsaturated polymer having a carboxylic acid group in the side chain, which has specific reaction between the support and the photosensitive layer to promot adhesion strength; improve printing durability, chemical resistance; laser recording, photothermography FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-7306893-B2 Intermediate layer contains a unsaturated polymer having a carboxylic acid group in the side chain, which has specific reaction between the support and the photosensitive layer to promot adhesion strength; improve printing durability, chemical resistance; laser recording, photothermography FUJIFILM CORPORATION (JP) 2007-12-11 US disclosed
US-20070218404-A1 Infrared-sensitive lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-20 US disclosed
EP-1834802-A1 Infrared-sensitive lithographic printing plate FUJIFILM Corporation (JP) 2007-09-19 EP disclosed