SCHEMBL14005138

SCHEMBL14005138

COc1ccc(C(OCCCCCCSSCCCCCCOP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.32
SLC6A1 P30531 2/20 0.32
SLC6A11 P48066 1/20 0.32
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16329608 0.94 SLC6A1 (0.34) KIF11SLC6A1SLC6A11KCNH2
SCHEMBL27050962 0.94 SLC6A1 (0.34) KIF11SLC6A1SLC6A11KCNH2
SCHEMBL2820572 0.94 SLC6A1 (0.34) KIF11SLC6A1SLC6A11KCNH2
SCHEMBL25764740 0.94 SLC6A1 (0.34) KIF11SLC6A1SLC6A11KCNH2
SCHEMBL31636266 0.93 SLC6A1 (0.31) SLC6A1SLC6A11
SCHEMBL2472575 0.92 SLC6A11 (0.35) KIF11SLC6A1SLC6A11KCNH2
SCHEMBL30116036 0.91 KIF11 (0.34) KIF11SLC6A1SLC6A11KCNH2
SCHEMBL30116106 0.91 KIF11 (0.34) KIF11SLC6A1SLC6A11KCNH2
SCHEMBL17166451 0.91 ALDH1A1 (0.33) SLC6A11
SCHEMBL8332233 0.88 ALDH1A1 (0.33) SLC6A1SLC6A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4729617-A1 APTAMER TARGETING CD25, DRUG CONJUGATE COMPRISING SAME, AND USE THEREOF Aptamer Sciences Inc. (KR) 2026-04-22 EP claimed
US-20260027147-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA LONZA SALES AG (CH) 2026-01-29 US claimed
US-20250382613-A1 METHODS OF USING EXTRACELLULAR VESICLE-ASO TARGETING STAT6 LONZA SALES AG (CH) 2025-12-18 US claimed
EP-4562156-A2 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA Lonza Sales AG (CH) 2025-06-04 EP claimed
EP-4547259-A2 METHODS OF USING EXTRACELLULAR VESICLE-ASO TARGETING STAT6 Lonza Sales AG (CH) 2025-05-07 EP claimed
CN-119948163-A CEBP/beta targeted extracellular vesicle-ASO constructs 隆萨销售股份有限公司 2025-05-06 CN claimed
US-20250101415-A1 DNA ORIGAMI STRUCTURE AND PROTEIN NANOPORE CONSTRUCT ILLUMINA, INC. 2025-03-27 US claimed
EP-4514997-A1 DNA ORIGAMI STRUCTURE AND PROTEIN NANOPORE CONSTRUCT ILLUMINA, INC. (US) 2025-03-05 EP claimed
US-20250049927-A1 MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF INTEROLIGO CORPORATION. (KR) 2025-02-13 US claimed
WO-2024257962-A1 APTAMER TARGETING CD25, DRUG CONJUGATE COMPRISING SAME, AND USE THEREOF 주식회사 압타머사이언스 2024-12-19 WO claimed
CN-114729327-A Extracellular vesicles with STAT3 antisense oligonucleotides 科迪亚克生物科学公司 2022-07-08 CN claimed
EP-4013876-A1 EXTRACELLULAR VESICLE-NLRP3 ANTAGONIST Codiak BioSciences, Inc. (US) 2022-06-22 EP claimed
EP-4013877-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING STAT6 Codiak BioSciences, Inc. (US) 2022-06-22 EP claimed
EP-4013875-A1 EXTRACELLULAR VESICLES WITH STAT3-ANTISENSE OLIGONUCLEOTIDES Codiak BioSciences, Inc. (US) 2022-06-22 EP claimed
EP-4013872-A1 EXTRACELLULAR VESICLES WITH ANTISENSE OLIGONUCLEOTIDES TARGETING KRAS Codiak BioSciences, Inc. (US) 2022-06-22 EP claimed
EP-4013878-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA Codiak BioSciences, Inc. (US) 2022-06-22 EP claimed
CN-114641570-A Extracellular vesicles with KRAS-targeted antisense oligonucleotides 科迪亚克生物科学公司 2022-06-17 CN claimed
CN-109863161-B Labeled polynucleotides useful for nucleic acid sequencing 豪夫迈·罗氏有限公司 2022-06-03 CN claimed
WO-2022076596-A9 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING STAT6 CODIAK BIOSCIENCES, INC. (US) 2022-05-12 WO claimed
WO-2022076596-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING STAT6 CODIAK BIOSCIENCES, INC. (US) 2022-04-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382613-A1 METHODS OF USING EXTRACELLULAR VESICLE-ASO TARGETING STAT6 STAT6, EXOSC5, STAT5B KIF11 1834/4885SLC6A1 3858/4885SLC6A11 3377/4885
US-20260027147-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA CEBPZ, OSBP, DIS3 KIF11 2898/4885SLC6A1 2858/4885SLC6A11 2326/4885
US-20250049927-A1 MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF DCLRE1B, DUT, DCTD KIF11 674/4885SLC6A1 3770/4885SLC6A11 3740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.