Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14013943 | 0.89 | TLR7 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL14013902 | 0.89 | TLR7 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL7094788 | 0.75 | GBA1 (0.40) | CHRNB2CHRNA4 | |
| SCHEMBL4573907 | 0.74 | RIPK1 (0.36) | RIPK1 | |
| SCHEMBL27150266 | 0.72 | KDM4E (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL4590891 | 0.72 | SIGMAR1 (0.43) | RIPK1 | |
| SCHEMBL10153638 | 0.70 | SIGMAR1 (0.46) | CHRNB2CHRNA4 | |
| SCHEMBL21374046 | 0.67 | CHRNB2 (0.47) | CHRNB2CHRNA4 | |
| SCHEMBL10763885 | 0.67 | ALDH1A1 (0.43) | CHRNB2CHRNA4LMNA | |
| SCHEMBL4574098 | 0.67 | RIPK1 (0.38) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |