SCHEMBL14060451

SCHEMBL14060451

CC(C)=CCC(C)/C=C(\C)CO

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.39
ALDH1A1 P00352 3/20 0.39
TRPA1 O75762 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
CYP3A4 P08684 2/20 0.37
MAPT P10636 2/20 0.35
UGT1A1 P22309 1/20 0.35
SQLE Q14534 5/20 0.35
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18425121 1.00 ALOX15 (0.39) ALOX15ALDH1A1TRPA1KMT2AMEN1
SCHEMBL14060452 1.00 ALOX15 (0.39) ALOX15ALDH1A1TRPA1KMT2AMEN1
SCHEMBL14146580 1.00 ALOX15 (0.39) ALOX15ALDH1A1TRPA1KMT2AMEN1
SCHEMBL11204922 0.80 ALOX15 (0.34) ALOX15ALDH1A1TSHR
SCHEMBL296671 0.77 TRPA1 (0.38) TRPA1
SCHEMBL346930 0.77 TRPA1 (0.38) TRPA1
SCHEMBL29216379 0.76 TRPA1 (0.37) TRPA1
SCHEMBL8528012 0.76 TRPA1 (0.37) TRPA1
SCHEMBL5909404 0.75
SCHEMBL5909402 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476570-B 6-isopropyl-2, 4-dimethylcyclohexen-1-ol compounds as fragrance ingredients 奇华顿股份有限公司 2022-06-07 CN claimed
EP-3490966-B1 6-ISOPROPYL-2,4-DIMETHYLCYCLOHEXEN-1-OL COMPOUNDS AS FRAGRANCE INGREDIENTS GIVAUDAN SA (CH) 2020-09-16 EP claimed
US-10400193-B2 2,4,7-trimethyloct-6-en-1-ol as fragrance ingredient GIVAUDAN S.A. (CH) 2019-09-03 US claimed
US-20190233357-A1 6-ISOPROPYL-2,4-DIMETHYLCYCLOHEXEN-1-OL COMPOUNDS AS FRAGRANCE INGREDIENTS GIVAUDAN SA (CH) 2019-08-01 US claimed
EP-3490966-A1 6-ISOPROPYL-2,4-DIMETHYLCYCLOHEXEN-1-OL COMPOUNDS AS FRAGRANCE INGREDIENTS Givaudan SA (CH) 2019-06-05 EP claimed
US-20180201872-A1 2,4,7-TRIMETHYLOCT-6-EN-1-OL AS FRAGANCE INGREDIENT GIVAUDAN S.A. (CH) 2018-07-19 US claimed
EP-3328822-A1 2,4,7-TRIMETHYLOCT-6-EN-1-OL AS FRAGANCE INGREDIENT Givaudan SA (CH) 2018-06-06 EP claimed
WO-2018019935-A1 6-ISOPROPYL-2,4-DIMETHYLCYCLOHEXEN-1-OL COMPOUNDS AS FRAGRANCE INGREDIENTS GIVAUDAN SA (CH) 2018-02-01 WO claimed
WO-2017017152-A1 2,4,7-TRIMETHYLOCT-6-EN-1-OL AS FRAGANCE INGREDIENT GIVAUDAN SA (CH) 2017-02-02 WO claimed
EP-2714633-B1 TERPENE ALCOHOLS FOR USE IN FRAGRANCE COMPOSITIONS AND PERFUMED PRODUCTS GIVAUDAN SA (CH) 2016-06-29 EP claimed
US-9120994-B2 Terpene alcohols for use in fragrance compositions and perfumed products GIVAUDAN S.A. (CH) 2015-09-01 US claimed
US-20150038386-A1 TERPENE ALCOHOLS FOR USE IN FRAGRANCE COMPOSITIONS AND PERFUMED PRODUCTS GIVAUDAN S.A. (CH) 2015-02-05 US claimed
WO-2012159223-A1 TRIMETHYLOCTADIENOL AND DERIVATIVES THEREOF USED AS FRAGRANCE INGREDIENT GIVAUDAN SA (CH) 2012-11-29 WO claimed
WO-2012160189-A1 TERPENE ALCOHOLS FOR USE IN FRAGRANCE COMPOSITIONS AND PERFUMED PRODUCTS GIVAUDAN SA (CH) 2012-11-29 WO claimed
EP-4581007-B1 DIMETHYLBICYCLOHEPTENYL AND DIMETHYLBICYCLOHEPTANYL DERIVATIVES AND THEIR USE AS ODORANTS GIVAUDAN SA (CH) 2026-05-27 EP disclosed
US-12612353-B2 Method for the production of musk fragrance ingredient GIVAUDAN SA (CH) 2026-04-28 US disclosed
US-12584153-B2 Enzyme-mediated process for making Amberketal and Amberketal homologues GIVAUDAN SA (CH) 2026-03-24 US disclosed
US-20150038386-A1 TERPENE ALCOHOLS FOR USE IN FRAGRANCE COMPOSITIONS AND PERFUMED PRODUCTS GIVAUDAN S.A. (CH) 2015-02-05 US disclosed
WO-2012160189-A1 TERPENE ALCOHOLS FOR USE IN FRAGRANCE COMPOSITIONS AND PERFUMED PRODUCTS GIVAUDAN SA (CH) 2012-11-29 WO disclosed
WO-2012159223-A1 TRIMETHYLOCTADIENOL AND DERIVATIVES THEREOF USED AS FRAGRANCE INGREDIENT GIVAUDAN SA (CH) 2012-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150038386-A1 TERPENE ALCOHOLS FOR USE IN FRAGRANCE COMPOSITIONS AND PERFUMED PRODUCTS ADH5, EBP, FASN ALOX15 394/4885ALDH1A1 172/4885TRPA1 21/4885
US-20180201872-A1 2,4,7-TRIMETHYLOCT-6-EN-1-OL AS FRAGANCE INGREDIENT TAS2R8, OR51E2, TAS2R50 ALOX15 25/4885ALDH1A1 591/4885TRPA1 61/4885
US-10400193-B2 2,4,7-trimethyloct-6-en-1-ol as fragrance ingredient ENO1, OR51E2, THOC2 ALOX15 8/4885ALDH1A1 273/4885TRPA1 25/4885
US-12612353-B2 Method for the production of musk fragrance ingredient ADH5, ADH1A, CYP51A1 ALOX15 975/4885ALDH1A1 101/4885TRPA1 737/4885
US-20190233357-A1 6-ISOPROPYL-2,4-DIMETHYLCYCLOHEXEN-1-OL COMPOUNDS AS FRAGRANCE INGREDIENTS TRPA1, TRPV1, NISCH ALOX15 220/4885ALDH1A1 177/4885TRPA1 1/4885
US-12584153-B2 Enzyme-mediated process for making Amberketal and Amberketal homologues ALKBH5, AMD1, ALKBH1 ALOX15 542/4885ALDH1A1 456/4885TRPA1 3965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.