SCHEMBL141982

SCHEMBL141982

CCCCC([C]=O)c1cccs1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.40
GLA P06280 1/20 0.40
TSHR P16473 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CTSK P43235 2/20 0.35
HDAC3 O15379 1/20 0.35
ALOX5 P09917 1/20 0.34
KDM4E B2RXH2 1/20 0.34
CCR1 P32246 1/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
KEAP1 Q14145 1/20 0.33
HSPA5 P11021 1/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11169009 0.95 HTT (0.36) HTTGLATSHRL3MBTL1CTSK
SCHEMBL142885 0.90 TAS1R3 (0.36) HTTGLATSHRL3MBTL1ALOX5
SCHEMBL144586 0.82 ALOX5 (0.38) HTTTSHRL3MBTL1ALOX5CES2
SCHEMBL23695275 0.77 CA2 (0.43) HTTGLATSHRL3MBTL1CTSK
SCHEMBL921560 0.77 HTT (0.42) HTTGLATSHRL3MBTL1CTSK
SCHEMBL7269210 0.75 NPC1 (0.50) HTTGLATSHRL3MBTL1CTSK
SCHEMBL7276887 0.75 NPC1 (0.50) HTTGLATSHRL3MBTL1CTSK
SCHEMBL175346 0.75 GLA (0.40) HTTGLATSHRL3MBTL1CTSK
SCHEMBL7284168 0.75 NPC1 (0.50) HTTGLATSHRL3MBTL1CTSK
SCHEMBL16334692 0.74 GLA (0.39) HTTGLATSHRL3MBTL1CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240084308-A1 FIBROTIC TREATMENT MONASH UNIVERSITY (AU) 2024-03-14 US disclosed
US-20240034845-A1 POLYMER PARTICLES QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2024-02-01 US disclosed
EP-3384549-B1 SODIUM-ION ELECTROLYTE COMPOSITION UNIV DEAKIN (AU) 2024-01-17 EP disclosed
US-11834663-B2 Fibrotic treatment MONASH UNIVERSITY (AU) 2023-12-05 US disclosed
US-20230348674-A1 HYDROGELS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2023-11-02 US disclosed
WO-2023190111-A1 RAFT POLYMERIZATION REACTION SOLUTION AND RAFT POLYMERIZATION REACTION SOLUTION PRODUCTION METHOD テクノUMG株式会社 2023-10-05 WO disclosed
CN-113939544-B non-core-shell polymer particles 悉尼大学 2023-08-22 CN disclosed
CN-116615468-A Polymer particles 昆士兰科技大学 2023-08-18 CN disclosed
WO-2023121483-A1 IMMUNOSTIMULATORY COMPOSITIONS VICTORIA LINK LIMITED (NZ) 2023-06-29 WO disclosed
WO-2023102600-A1 SYNTHESIS OF AMPHIPHILIC BLOCK COPOLYMERS AND POLYMERIC NANOFIBERS PRODUCED THEREFROM NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2023-06-15 WO disclosed
US-4981847-A Tricyclic compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-01-01 US disclosed
EP-0336230-A2 Cyclic peptide antagonists of Substance P and Substance K FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-10-11 EP disclosed
US-4497738-A Analogous compounds of cephalosporins, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-02-05 US disclosed
US-4473566-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-09-25 US disclosed
EP-0017138-B1 ANALOGOUS COMPOUNDS OF CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-07-04 EP disclosed
EP-0070575-A2 New starting compounds for preparing analogous compounds of cephalosporins and processes for their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-01-26 EP disclosed
US-4339449-A Analogous compounds of cephalosporins, and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1982-07-13 US disclosed
US-4254117-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-03-03 US disclosed
EP-0017138-A2 Analogous compounds of cephalosporins, processes for their preparation, and pharmaceutical composition containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-10-15 EP disclosed
US-4143166-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834663-B2 Fibrotic treatment MMP1, ENPEP, RNPEP HTT 4142/4885GLA 347/4885TSHR 2551/4885
US-20230348674-A1 HYDROGELS PHYKPL, TST, PHOSPHO1 HTT 2811/4885GLA 3841/4885TSHR 1684/4885
US-20240084308-A1 FIBROTIC TREATMENT MMP1, ENPEP, RNPEP HTT 4142/4885GLA 347/4885TSHR 2551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.