SCHEMBL14355671

SCHEMBL14355671

CC(C)CCCC(=O)NC(C)C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.61
MEN1 O00255 1/20 0.61
MAPK1 P28482 1/20 0.61
KMT2A Q03164 1/20 0.61
PLA2G10 O15496 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.41
HPGD P15428 3/20 0.41
NLRP1 Q9C000 1/20 0.41
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 2/20 0.40
EPHX2 P34913 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA1 P00915 2/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 1/20 0.38
KDM4C Q9H3R0 2/20 0.38
KDM4A O75164 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
CETP P11597 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14355670 0.93 FAAH (0.64) FAAHMEN1MAPK1KMT2APLA2G10
SCHEMBL7228998 0.91 KMT2A (0.68) FAAHMEN1MAPK1KMT2APLA2G10
SCHEMBL19196519 0.91 KMT2A (0.68) FAAHMEN1MAPK1KMT2APLA2G10
SCHEMBL13599197 0.91 KMT2A (0.68) FAAHMEN1MAPK1KMT2APLA2G10
SCHEMBL23031242 0.91 KMT2A (0.68) FAAHMEN1MAPK1KMT2APLA2G10
SCHEMBL23031241 0.91 KMT2A (0.68) FAAHMEN1MAPK1KMT2APLA2G10
SCHEMBL10258138 0.91 KMT2A (0.68) FAAHMEN1MAPK1KMT2APLA2G10
SCHEMBL21189948 0.91 KMT2A (0.68) FAAHMEN1MAPK1KMT2APLA2G10
SCHEMBL8909364 0.86 MEN1 (0.54) FAAHMEN1MAPK1KMT2APLA2G10
SCHEMBL5909190 0.85 FAAH (0.71) FAAHMEN1MAPK1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827744-B2 Bottlebrush copolymers and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-11-28 US disclosed
US-20230295437-A1 SILICON CONTAINING DETECTABLE COMPOUNDS Singular Genomics Systems, Inc. 2023-09-21 US disclosed
US-20230295437-A1 SILICON CONTAINING DETECTABLE COMPOUNDS Singular Genomics Systems, Inc. 2023-09-21 US disclosed
US-11697736-B2 Silicon containing detectable compounds Singular Genomics Systems, Inc. (US) 2023-07-11 US disclosed
US-11697736-B2 Silicon containing detectable compounds Singular Genomics Systems, Inc. (US) 2023-07-11 US disclosed
US-20230158169-A1 LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE AUDAX PRIVATE DEBT LLC, AS AGENT 2023-05-25 US disclosed
US-20230158169-A1 LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE AUDAX PRIVATE DEBT LLC, AS AGENT 2023-05-25 US disclosed
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid SHIONOGI & CO., LTD. (JP) 2023-05-02 US disclosed
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid SHIONOGI & CO., LTD. (JP) 2023-05-02 US disclosed
US-20230054270-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) 2023-02-23 US disclosed
US-20200384010-A1 COMPLEX OF NUCLEIC ACID MEDICINE AND MULTIBRANCHED LIPID SHIONOGI & CO., LTD. (JP) 2020-12-10 US disclosed
US-20190352508-A1 SILICON CONTAINING DETECTABLE COMPOUNDS FIRST-CITIZENS BANK & TRUST COMPANY 2019-11-21 US disclosed
US-20180094099-A1 BOTTLEBRUSH COPOLYMERS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-04-05 US disclosed
US-9809824-B2 CpG oligonucleotide prodrugs, compositions thereof and associated therapeutic methods THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2017-11-07 US disclosed
US-9630945-B2 Autotaxin inhibitors NOVARTIS AG (CH) 2017-04-25 US disclosed
US-20160304473-A1 EXCIMER FORMING COMPOUNDS THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2016-10-20 US disclosed
US-9156830-B2 Heterocyclic compounds SHIONOGI & CO., LTD. (JP) 2015-10-13 US disclosed
US-20140249159-A1 HETEROCYCLIC COMPOUNDS PURDUE PHARMA L.P. 2014-09-04 US disclosed
US-7301037-B2 Charged compounds comprising a nucleic acid binding moiety and uses therefor GENESOFT, INC. (US) 2007-11-27 US disclosed
US-20070105135-A1 Charged compounds comprising a nucleic acid binding moiety and uses therefor GENESOFT PHARMACEUTICALS, INC. (US) 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11697736-B2 Silicon containing detectable compounds AS3MT, SCLY, NASP FAAH 4634/4885MEN1 660/4885MAPK1 4604/4885
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid FABP1, POLRMT, SREBF1 FAAH 1579/4885MEN1 1693/4885MAPK1 4801/4885
US-20200384010-A1 COMPLEX OF NUCLEIC ACID MEDICINE AND MULTIBRANCHED LIPID FABP1, POLRMT, SREBF1 FAAH 1579/4885MEN1 1693/4885MAPK1 4801/4885
US-20070105135-A1 Charged compounds comprising a nucleic acid binding moiety and uses therefor POLRMT, PCNA, SARS1 FAAH 4532/4885MEN1 3152/4885MAPK1 3537/4885
US-20230295437-A1 SILICON CONTAINING DETECTABLE COMPOUNDS AS3MT, SCLY, NASP FAAH 4634/4885MEN1 660/4885MAPK1 4604/4885
US-20180094099-A1 BOTTLEBRUSH COPOLYMERS AND USES THEREOF TRIB1, TRIB2, ABCB11 FAAH 839/4885MEN1 4342/4885MAPK1 4048/4885
US-11827744-B2 Bottlebrush copolymers and uses thereof TRIB1, TRIB2, ABCB11 FAAH 839/4885MEN1 4342/4885MAPK1 4048/4885
US-20140249159-A1 HETEROCYCLIC COMPOUNDS HRH2, UGT1A3, UGT1A1 FAAH 887/4885MEN1 3182/4885MAPK1 1749/4885
US-20190352508-A1 SILICON CONTAINING DETECTABLE COMPOUNDS AS3MT, SCLY, NASP FAAH 4634/4885MEN1 660/4885MAPK1 4604/4885
US-20230158169-A1 LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE CTSA, CTSS, CTSV FAAH 645/4885MEN1 3517/4885MAPK1 4666/4885
US-20160304473-A1 EXCIMER FORMING COMPOUNDS PHAX, RNMT, POLM FAAH 4592/4885MEN1 2014/4885MAPK1 1867/4885
US-20230054270-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AR, SHBG, NR5A1 FAAH 2789/4885MEN1 1287/4885MAPK1 3770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.