SCHEMBL1439290

SCHEMBL1439290

CC(C)COC(=O)CC1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.46
ALDH1A1 P00352 2/20 0.42
RAB9A P51151 1/20 0.41
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
KMT2A Q03164 2/20 0.39
EPHX1 P07099 1/20 0.39
HPGD P15428 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1439757 0.98 L3MBTL1 (0.47) L3MBTL1ALDH1A1RAB9ALMNATDP1
SCHEMBL19926076 0.90 TSHR (0.41) L3MBTL1ALDH1A1RAB9ALMNATDP1
SCHEMBL6677700 0.86 L3MBTL1 (0.44) L3MBTL1ALDH1A1LMNATDP1KMT2A
SCHEMBL5572124 0.84 L3MBTL1 (0.45) L3MBTL1ALDH1A1LMNATDP1KMT2A
SCHEMBL11125921 0.83 L3MBTL1 (0.42) L3MBTL1ALDH1A1LMNATDP1KMT2A
SCHEMBL27295498 0.82 SLC6A1 (0.38) L3MBTL1ALDH1A1RAB9ATDP1EPHX1
SCHEMBL17928311 0.80 L3MBTL1 (0.45) L3MBTL1ALDH1A1LMNATDP1KMT2A
SCHEMBL29136168 0.80 MEN1 (0.48) L3MBTL1ALDH1A1LMNATDP1KMT2A
SCHEMBL1401342 0.80 L3MBTL1 (0.42) L3MBTL1ALDH1A1TDP1KMT2A
SCHEMBL25311355 0.79 TDP1 (0.50) L3MBTL1ALDH1A1LMNATDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080221003-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-09-11 US claimed
US-20080207481-A1 CONSUMER PRODUCTS HAVING VARYING ODORS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-28 US claimed
US-5491167-A INHIBITORS OF CHOLESTEROL BIOSYNTHESIS SANKYO COMPANY, LIMITED (JP) 1996-02-13 US claimed
US-20240067651-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS BIOHAVEN THERAPEUTICS LTD. 2024-02-29 US disclosed
US-9719058-B2 Fragrant oil encapsulation PAPIERFABRIK AUGUST KOEHLER SE (DE) 2017-08-01 US disclosed
CN-103145553-B Synthesis and application of 2, 3-alkyl substituted diester succinate DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2016-06-01 CN disclosed
US-20150361107-A1 ORALLY BIOAVAILABLE BETA-LACTAMASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-12-17 US disclosed
US-20150210965-A1 FRAGRANT OIL ENCAPSULATION SYMRISE AG (DE) 2015-07-30 US disclosed
CN-103145553-A Synthesis and application of 2, 3-alkyl substituted diester succinate UNIV DALIAN TECH 2013-06-12 CN disclosed
US-20130023504-A1 Modulation of Prostaglandin/Cyclooxygenase Metabolic Pathways HUNTER-FLEMING LIMITED (GB) 2013-01-24 US disclosed
US-20120308486-A1 Fragrance and/or flavoring compositions containing dioxolanes SYMRISE AG (DE) 2012-12-06 US disclosed
EP-0570245-A2 Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition, their preparation and use SANKYO COMPANY LIMITED (JP) 1993-11-18 EP disclosed
US-5242914-A 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics SANKYO COMPANY, LIMITED (JP) 1993-09-07 US disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed
EP-0518558-A1 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics Sankyo Company Limited (JP) 1992-12-16 EP disclosed
US-5104867-A 2-(HETEROCYCLYLTHIO)CARBAPENEM DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIBIOTICS SANKYO COMPANY, LIMITED (JP) 1992-04-14 US disclosed
EP-0443883-A1 Carbapenem derivatives having antibiotic activity, their preparation and their use Sankyo Company Limited (JP) 1991-08-28 EP disclosed
EP-0437016-A2 Lipid A analogues having immunoactivating and anti-tumour activity Sankyo Company Limited (JP) 1991-07-17 EP disclosed
EP-0363223-A2 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use Sankyo Company Limited (JP) 1990-04-11 EP disclosed
EP-0337637-A1 2-(Heterocyclylthio)carbapenem derivatives their preparation and their use as antibiotics Sankyo Company Limited (JP) 1989-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023504-A1 Modulation of Prostaglandin/Cyclooxygenase Metabolic Pathways PTGES2, PTGES, PTGS2 L3MBTL1 4192/4885ALDH1A1 804/4885RAB9A 4302/4885
US-20120308486-A1 Fragrance and/or flavoring compositions containing dioxolanes FDFT1, DECR1, DOHH L3MBTL1 4861/4885ALDH1A1 69/4885RAB9A 4531/4885
US-20240067651-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS MPO, CAT, SOD1 L3MBTL1 2182/4885ALDH1A1 570/4885RAB9A 2417/4885
US-20150361107-A1 ORALLY BIOAVAILABLE BETA-LACTAMASE INHIBITORS SI, ALPI, GAA L3MBTL1 214/4885ALDH1A1 273/4885RAB9A 1272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.