Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 9/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14423937 | 0.82 | PTPN1 (0.44) | PPARGPPARAALDH1A1MAPTHPGD | |
| SCHEMBL14423923 | 0.72 | AKR1C3 (0.58) | ALDH1A1MAPTHDAC2HDAC8HDAC6 | |
| SCHEMBL14423936 | 0.72 | PIM1 (0.48) | MEN1KMT2A | |
| SCHEMBL14198605 | 0.71 | CA2 (0.57) | CA2PPARGPPARDPPARAMAPT | |
| SCHEMBL8548650 | 0.71 | ALDH1A1 (0.55) | CA2ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL14423939 | 0.69 | HDAC1 (0.44) | ALDH1A1MAPTHPGDHDAC3HDAC4 | |
| SCHEMBL14423938 | 0.68 | PGR (0.43) | ALDH1A1MAPTHPGDHDAC1HDAC8 | |
| SCHEMBL22480924 | 0.63 | CA2 (0.60) | CA2PPARGPPARDPPARA | |
| SCHEMBL28374908 | 0.61 | PGR (0.58) | ALDH1A1MAPTHPGDHDAC2HDAC8 | |
| SCHEMBL11153552 | 0.59 | PPARG (0.47) | CA2PPARGPPARDPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262318-B2 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER, INC. (US) | 2007-08-28 | — | — | US | disclosed |