Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14423934 | 0.82 | CA2 (0.40) | ALDH1A1PPARAMAPTMEN1HPGD | |
| SCHEMBL14198604 | 0.74 | MAPT (0.54) | PTPN1ALDH1A1NPSR1MAOACISD1 | |
| SCHEMBL14423938 | 0.73 | PGR (0.43) | ALDH1A1HTR6RORCMAPTKDM4E | |
| SCHEMBL14423923 | 0.71 | AKR1C3 (0.58) | PTPN1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL14423936 | 0.71 | PIM1 (0.48) | MAOACISD1MAOBMEN1KMT2A | |
| SCHEMBL14423939 | 0.68 | HDAC1 (0.44) | ALDH1A1HTR6PIK3CAMAPTMEN1 | |
| SCHEMBL10085681 | 0.67 | MAOA (0.57) | PTPN1ALDH1A1NPSR1MAOACISD1 | |
| SCHEMBL1519948 | 0.66 | MAPT (0.68) | PTPN1ALDH1A1NPSR1MAOACISD1 | |
| SCHEMBL6074864 | 0.65 | ALDH1A1 (0.47) | ALDH1A1HTR6MAPTMEN1LMNA | |
| SCHEMBL1247602 | 0.65 | PPARG (0.66) | PTPN1ALDH1A1NPSR1MAOACISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262318-B2 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER, INC. (US) | 2007-08-28 | — | — | US | disclosed |