Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.62 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.52 |
| ▸ | ESR2 known ✓ | Q92731 | 3/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.62 |
| ▸ | FNTA | P49354 | 1/20 | 0.61 |
| ▸ | FNTB | P49356 | 1/20 | 0.61 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10958914 | 0.95 | CA2 (0.62) | CA2CAMK2AFNTAFNTBCA1 | |
| Potassium Ion SCHEMBL10912220 | 0.95 | CA2 (0.62) | CA2CAMK2AFNTAFNTBCA1 | |
| Lithium Ion SCHEMBL3811946 | 0.95 | CA2 (0.62) | CA2CAMK2AFNTAFNTBCA1 | |
| Hydroxyphenyl Propionic Acid SCHEMBL10954581 | 0.79 | ESR1 (0.54) | CA2CAMK2AFNTAFNTBCA1 | |
| Bicarbonate SCHEMBL27669090 | 0.79 | CA2 (0.83) | CA2CAMK2AFNTAFNTBCTBP2 | |
| SCHEMBL7150590 | 0.79 | CA2 (0.68) | CA2CAMK2AFNTAFNTBCA1 | |
| SCHEMBL9644305 | 0.78 | TDP1 (0.46) | CA2CA1CES2CES1 | |
| SCHEMBL17003351 | 0.78 | CA2 (0.54) | CA2CAMK2AFNTAFNTBCA1 | |
| 4-Hydroxyphenylpyruvic Acid SCHEMBL24157 | 0.78 | FNTA (0.72) | CA2CAMK2AFNTAFNTBCTBP2 | |
| SCHEMBL3787818 | 0.78 | CA1 (0.54) | CA2CA1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010679-B | Synthesis method of water-soluble benzoxazine | 濮阳市恩赢高分子材料有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-114085343-A | Modified sulfonated phenolic resin filtrate reducer for drilling fluid and preparation method thereof | 中石化石油工程技术服务有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-106554266-B | Preparation method of methoxyphenylacetic acid, intermediate thereof and salt thereof | 联化科技(盐城)有限公司 | 2020-02-11 | — | — | CN | claimed |
| US-5500668-A | INK JET PRINTING | XEROX CORPORATION (US) | 1996-03-19 | — | — | US | claimed |
| CN-116622354-B | Biological chelating agent, scale remover and method for removing biological sulfide scale of oil and gas reservoir | 中国石油天然气集团有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-115010679-B | Synthesis method of water-soluble benzoxazine | 濮阳市恩赢高分子材料有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-116622354-A | Biological chelating agent, scale remover and method for removing biological sulfide scale of oil and gas reservoir | 中国石油天然气集团有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-114796246-B | Medicine for treating heart failure and application thereof | 佳木斯大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-110652585-B | Polysaccharide-protein conjugate immune preparation and application thereof | 武汉博沃生物科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-115010679-A | Synthetic method of water-soluble benzoxazine | 濮阳市恩赢高分子材料有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-114796246-A | Medicine for treating heart failure and application thereof | 佳木斯大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114085343-A | Modified sulfonated phenolic resin filtrate reducer for drilling fluid and preparation method thereof | 中石化石油工程技术服务有限公司 | 2022-02-25 | — | — | CN | disclosed |
| EP-1355673-A2 | MULTIVALENT MENINGOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE VACCINE | Aventis Pasteur (US) | 2003-10-29 | — | — | EP | disclosed |
| US-20030068336-A1 | Purified capsular polysaccharides from Neisseria meningitidis serogroups are activated and attached to a carriers protein | SANOFI PASTEUR INC. | 2003-04-10 | — | — | US | disclosed |
| WO-2002058737-A2 | MULTIVALENT MENINGOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE VACCINE | AVENTIS PASTEUR (US) | 2002-08-01 | — | — | WO | disclosed |
| US-6350795-B1 | ACOUSTIC PHASE-CHANGE CONDUCTIVE INK CONTAINING LOW MOLECULAR WEIGHT OXYALKYLENE SEGMENTS COMPLEXED WITH UREA DERIVATIVES | XEROX CORPORATION | 2002-02-26 | — | — | US | disclosed |
| US-6096125-A | Ink compositions | XEROX CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| US-5500668-A | INK JET PRINTING | XEROX CORPORATION (US) | 1996-03-19 | — | — | US | disclosed |
| US-4537724-A | Alkanoyloxybenzenesulfonate salt production | ETHYL CORPORATION (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0125641-A2 | Alkanoyloxybenzenesulfonate salt production | ETHYL CORPORATION (US) | 1984-11-21 | — | — | EP | disclosed |