Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | QDPR | P09417 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | YWHAG | P61981 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.31 |
| ▸ | PGF | P49763 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747175 | 0.87 | MEN1 (0.41) | MEN1GAAKMT2APOLBGFER | |
| SCHEMBL28231046 | 0.86 | ESR1 (0.42) | MEN1GAAKMT2APOLBGFER | |
| SCHEMBL2746967 | 0.85 | MEN1 (0.41) | MEN1GAAKMT2APOLBGFER | |
| SCHEMBL2747207 | 0.78 | ESR2 (0.45) | MEN1GAAKMT2APOLBGFER | |
| SCHEMBL28956093 | 0.74 | ALDH1A1 (0.35) | CYP3A4TSHRBACE1ALDH1A1LMNA | |
| SCHEMBL2748102 | 0.72 | MEN1 (0.31) | MEN1GAAKMT2APOLBGFER | |
| SCHEMBL559964 | 0.72 | MEN1 (1.00) | MEN1GAAKMT2APOLBGFER | |
| SCHEMBL2748795 | 0.72 | LIG1 (0.38) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL28205290 | 0.72 | ALDH1A1 (0.53) | MEN1GAAKMT2APOLBGFER | |
| SCHEMBL2747640 | 0.71 | MMP2 (0.38) | MEN1GAAKMT2APOLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012555-A1 | Compounds, Compositions and Methods for the Treatment of Islet Amyloid Polypeptide (IAPP) Accumulation in Diabetes | PROTAMED, INC. | 2013-01-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012555-A1 | Compounds, Compositions and Methods for the Treatment of Islet Amyloid Polypeptide (IAPP) Accumulation in Diabetes | IAPP, AMY2A, IDE | MEN1 1247/4885GAA 48/4885KMT2A 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.