Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | GPR6 | P46095 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397188 | 0.83 | CTSC (0.49) | HDAC1TSHRGAA | |
| SCHEMBL6204294 | 0.80 | ALDH1A1 (0.51) | HTTALDH1A1HDAC1HDAC6GPR6 | |
| SCHEMBL13570425 | 0.79 | ITGB3 (0.52) | ALDH1A1SMN1; SMN2ITGB3ITGAVITGA2B | |
| SCHEMBL29129911 | 0.78 | ITGB3 (0.59) | ALDH1A1ITGB3ITGAVITGA2BCHRNB2 | |
| SCHEMBL28570403 | 0.78 | ITGB3 (0.59) | ALDH1A1ITGB3ITGAVITGA2BCHRNB2 | |
| Niacin SCHEMBL29993073 | 0.78 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2ITGB3ITGAVITGA2B | |
| SCHEMBL6203419 | 0.78 | HDAC1 (0.49) | ALDH1A1HDAC1HDAC6MAPT | |
| SCHEMBL3456328 | 0.77 | MAPT (0.51) | HTTALDH1A1MAPTSMN1; SMN2ITGB3 | |
| SCHEMBL1543355 | 0.77 | GRM5 (0.52) | HTTALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| Niacin SCHEMBL18244432 | 0.76 | CHRNB2 (0.44) | ALDH1A1L3MBTL1MAPTSMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070128145-A1 | Amino acid adducts for percutaneous delivery of vitamin B3 | THE PROCTER & GAMBLE COMPANY | 2007-06-07 | — | — | US | disclosed |
| US-20070128145-A1 | Amino acid adducts for percutaneous delivery of vitamin B3 | THE PROCTER & GAMBLE COMPANY | 2007-06-07 | — | — | US | disclosed |
| WO-2007064762-A2 | CONJUGATES OF AMINO ACIDS AND VITAMIN B3 FOR PERCUTANEOUS DELIVERY OF VITAMIN B3 | THE PROCTER & GAMBLE COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |
| EP-1792630-A1 | Conjugates of amino acids and vitamin B3 for percutaneous delivery of vitamin B3 | The Procter & Gamble Company (US) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070128145-A1 | Amino acid adducts for percutaneous delivery of vitamin B3 | SLC1A5, SLC19A1, PLPBP | HTT 3440/4885ALDH1A1 1215/4885HDAC1 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.