SCHEMBL14543737

SCHEMBL14543737

O=C(OCCC1CCCCC1)c1ccc(S(=O)(=O)O)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 5/20 0.43
TDP1 Q9NUW8 4/20 0.43
THRB P10828 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
APEX1 P27695 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SCN9A Q15858 4/20 0.39
PTGS2 P35354 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
HPGD P15428 1/20 0.38
PAX8 Q06710 1/20 0.38
POLB P06746 1/20 0.37
HTT P42858 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14543736 0.87 HTR7 (0.43) KMT2AALDH1A1TDP1THRBL3MBTL1
SCHEMBL14543740 0.85 SCN9A (0.40) KMT2AALDH1A1TDP1L3MBTL1SCN9A
SCHEMBL14543790 0.83 RAB9A (0.39) KMT2AALDH1A1TDP1L3MBTL1SCN9A
SCHEMBL14543738 0.83 THRB (0.57) KMT2ATHRBL3MBTL1LMNAPAX8
SCHEMBL14883129 0.82 ALDH1A1 (0.46) KMT2AALDH1A1TDP1L3MBTL1PTGS2
SCHEMBL14543772 0.81 CA1 (0.43) KMT2AALDH1A1SCN9ALMNAHPGD
SCHEMBL6391684 0.81 ALDH1A1 (0.44) KMT2AALDH1A1TDP1THRBNPSR1
SCHEMBL250654 0.80 KMT2A (0.47) KMT2AALDH1A1TDP1MAPK1POLB
SCHEMBL6837846 0.79 SMN1; SMN2 (0.46) KMT2AALDH1A1TDP1L3MBTL1CHRM2
SCHEMBL3423895 0.78 KMT2A (0.46) KMT2AALDH1A1TDP1MAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927194-B2 Chemical amplified photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-06 US disclosed
US-20070088131-A1 Sulfonate and resist composition TOISHI KOUJI 2007-04-19 US disclosed
US-7205090-B2 Chemical amplification type positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-17 US disclosed
US-7175963-B2 Chemical amplification type positive resist composition and a resin therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-13 US disclosed