Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.64 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29943511 | 1.00 | GPR3 (0.64) | GPR3CHEK1PTPRCMEN1KMT2A | |
| SCHEMBL29726026 | 0.89 | S100A4 (0.46) | GPR3CHEK1PTPRCCA12CA9 | |
| SCHEMBL1326395 | 0.89 | S100A4 (0.46) | GPR3CHEK1PTPRCCA12CA9 | |
| SCHEMBL17322541 | 0.88 | GPR3 (0.64) | GPR3CHEK1PTPRCMEN1KMT2A | |
| SCHEMBL30481783 | 0.88 | GPR3 (0.64) | GPR3CHEK1PTPRCMEN1KMT2A | |
| SCHEMBL21832063 | 0.86 | S100A4 (0.45) | GPR3CHEK1PTPRCCA12CA9 | |
| SCHEMBL25990047 | 0.85 | GPR3 (0.55) | GPR3CHEK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25989992 | 0.82 | ALDH1A1 (0.47) | GPR3CHEK1PTPRCMEN1KMT2A | |
| SCHEMBL25989968 | 0.82 | ALDH1A1 (0.47) | GPR3CHEK1PTPRCMEN1KMT2A | |
| SCHEMBL20979980 | 0.81 | GPR3 (0.46) | GPR3PTPRCMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023152063-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-08-17 | — | — | WO | disclosed |
| US-20160235869-A1 | DERIVATIVES OF DIBENZOTHIOPHENE IMAGING OF alpha-7 NICOTINIC ACETYLCHOLINE RECEPTORS | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-08-18 | — | — | US | disclosed |
| US-9397301-B2 | Sulfone group-containing compound, an organic light emitting diode (OLED) device having the same, and a method of fabricating the OLED device | SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) | 2016-07-19 | — | — | US | disclosed |
| US-9397301-B2 | Sulfone group-containing compound, an organic light emitting diode (OLED) device having the same, and a method of fabricating the OLED device | SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) | 2016-07-19 | — | — | US | disclosed |
| US-20160111653-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-04-21 | — | — | US | disclosed |
| US-20160111653-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-04-21 | — | — | US | disclosed |
| US-20150357584-A1 | A Sulfone Group-Containing Compound, An Organic Light Emitting Diode (OLED) Device Using The Same, and A Method of Fabricating the OLED Device | SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2015-12-10 | — | — | US | disclosed |
| US-20150357584-A1 | A Sulfone Group-Containing Compound, An Organic Light Emitting Diode (OLED) Device Using The Same, and A Method of Fabricating the OLED Device | SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2015-12-10 | — | — | US | disclosed |
| US-8846661-B2 | Diazahomoadamantane derivatives and methods of use thereof | ABBVIE INC. (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2443122-B1 | DIAZAHOMOADAMANTANE DERIVATIVES AND METHODS OF USE THEREOF | ABBVIE INC (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2258682-A2 | Amino-substituted tricyclic derivatives and methods of use | Abbott Laboratories (US) | 2010-12-08 | — | — | EP | disclosed |
| US-7838612-B2 | Arylene fluorinated sulfonimide compositions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-23 | — | — | US | disclosed |
| US-20090136817-A1 | ARYLENE FLUORINATED SULFONIMIDE POLYMERS AND MEMBRANES | U.S. DEPARTMENT OF ENERGY | 2009-05-28 | — | — | US | disclosed |
| US-20080214732-A1 | PROCESS FOR THE PREPARATION OF ARYLENE FLUORINATED SULFONIMIDE POLYMERS AND MEMBRANES | U.S. DEPARTMENT OF ENERGY | 2008-09-04 | — | — | US | disclosed |
| US-20080177088-A1 | ARYLENE FLUORINATED SULFONIMIDE COMPOSITIONS | U.S. DEPARTMENT OF ENERGY | 2008-07-24 | — | — | US | disclosed |
| US-20080161281-A1 | Amino-Substituted Tricyclic Derivatives and Methods of Use | ABBOTT LABORATORIES (US) | 2008-07-03 | — | — | US | disclosed |
| US-7365193-B2 | Amino-substituted tricyclic derivatives and methods of use | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| EP-1711463-A2 | AMINO-SUBSTITUTED TRICYCLIC DERIVATIVES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2006-10-18 | — | — | EP | disclosed |
| US-20050234031-A1 | Amino-substituted tricyclic derivatives and methods of use | ABBVIE INC. | 2005-10-20 | — | — | US | disclosed |
| WO-2005077899-A2 | AMINO-SUBSTITUTED TRICYCLIC DERIVATIVES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234031-A1 | Amino-substituted tricyclic derivatives and methods of use | CHRNA1, CHRM1, GALR1 | GPR3 142/4885CHEK1 1547/4885PTPRC 3010/4885 |
| US-20080177088-A1 | ARYLENE FLUORINATED SULFONIMIDE COMPOSITIONS | FES, FLNA, FLNB | GPR3 3308/4885CHEK1 1902/4885PTPRC 1539/4885 |
| US-20150357584-A1 | A Sulfone Group-Containing Compound, An Organic Light Emitting Diode (OLED) Device Using The Same, and A Method of Fabricating the OLED Device | OCIAD1, SULT1A1, STARD10 | GPR3 1163/4885CHEK1 2844/4885PTPRC 4550/4885 |
| US-20160235869-A1 | DERIVATIVES OF DIBENZOTHIOPHENE IMAGING OF alpha-7 NICOTINIC ACETYLCHOLINE RECEPTORS | CHRNA7, CHRNB2, CHRNB3 | GPR3 256/4885CHEK1 1984/4885PTPRC 3301/4885 |
| US-20080161281-A1 | Amino-Substituted Tricyclic Derivatives and Methods of Use | CHRNA1, CHRM1, CHRNB1 | GPR3 120/4885CHEK1 1347/4885PTPRC 3270/4885 |
| US-20160111653-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | PIEZO1, TMEM109, KCNN2 | GPR3 4132/4885CHEK1 4705/4885PTPRC 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.