Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907524 | 0.85 | PIK3R1 (0.33) | NFE2L2 | |
| SCHEMBL433493 | 0.82 | ALDH1A1 (0.37) | GPR3HPGDIDO1KDM4EALDH1A1 | |
| SCHEMBL432357 | 0.81 | GABRP (0.41) | GPR3PTPN1NPC1PTPRCHPGD | |
| SCHEMBL2013259 | 0.81 | GPR3 (0.39) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL8129685 | 0.81 | PDE10A (0.36) | CASP3SENP8SENP7SENP6GPR3 | |
| SCHEMBL9138237 | 0.81 | HSD11B1 (0.41) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL8077591 | 0.81 | PTGS2 (0.36) | GPR3HPGDALDH1A1CYP2A6 | |
| SCHEMBL2225126 | 0.81 | ALDH1A1 (0.38) | GPR3NPC1RAB9AIDO1ALDH1A1 | |
| SCHEMBL8123605 | 0.80 | RAB9A (0.46) | L3MBTL1GPR3NPC1HPGDRAB9A | |
| SCHEMBL9136686 | 0.79 | ACMSD (0.38) | L3MBTL1PTPN1NPC1PTPRCHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547701-B2 | Haloalkyl containing compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2009-06-16 | — | — | US | claimed |
| US-20050182096-A1 | Haloalkyl containing compounds as cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-08-18 | — | — | US | claimed |
| CN-113200901-A | Aziridine-2-yl- (aryl) ketone derivative and preparation method thereof | 上海应用技术大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-110467549-A | A kind of N substitution 2- aminomethyl-1,2, the preparation method of 3,5- triaryl pentane -1,5- diketone | SHANGHAI INST TECH | 2019-11-19 | — | — | CN | disclosed |
| CN-110407739-A | A kind of preparation method of (4,6- diaryl-tetrahydropyridine -3- base) (aryl) ketone | SHANGHAI INST TECH | 2019-11-05 | — | — | CN | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2004065372-A1 | TETRAZOLE-FUNCTIONALIZED AMINO ACIDS, THEIR PRODUCTION AND USE | MEDIGENE AKTIENGESELLSCHAFT (DE) | 2004-08-05 | — | — | WO | disclosed |
| CN-1058841-C | Fungicidal oxazolidinones | DU PONT (US) | 2000-11-29 | — | — | CN | disclosed |
| WO-1998029411-A1 | SULFONAMIDE COMPOUNDS HAVING 5-HT RECEPTOR ACTIVITY | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-07-09 | — | — | WO | disclosed |
| US-5466821-A | Triazole ring containing fungicides, intermediates | ZENECA LIMITED (GB) | 1995-11-14 | — | — | US | disclosed |
| CN-1028143-C | Oxazolidinone sterilization composition | DU PONT (US) | 1995-04-12 | — | — | CN | disclosed |
| US-5395942-A | Fungicides for plants | ZENECA LIMITED (GB) | 1995-03-07 | — | — | US | disclosed |
| CN-1096157-A | Antifungal De oxazolidone | DU PONT (US) | 1994-12-14 | — | — | CN | disclosed |
| US-5204363-A | Plant fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-04-20 | — | — | US | disclosed |
| US-5156669-A | Fungicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-20 | — | — | US | disclosed |
| US-5004494-A | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-02 | — | — | US | disclosed |
| CN-1047079-A | FUNGICIDAL OXAZOLIDINONES | DU PONT (US) | 1990-11-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182096-A1 | Haloalkyl containing compounds as cysteine protease inhibitors | CTSF, CTSS, CTSE | L3MBTL1 1367/4885CASP3 1154/4885SENP8 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.