Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775936 | 0.83 | FBP1 (0.37) | ALOX5ALDH1A1L3MBTL1GAAPOLB | |
| SCHEMBL14775910 | 0.78 | FTO (0.35) | HPGDALDH1A1FEN1 | |
| SCHEMBL12082558 | 0.75 | LMNA (0.47) | LMNAALOX15MAPTMEN1KMT2A | |
| SCHEMBL12082374 | 0.74 | PKM (0.47) | LMNAALOX15MAPTMEN1KMT2A | |
| SCHEMBL14775713 | 0.74 | PKM (0.32) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL9489749 | 0.72 | IMPDH2 (0.38) | MAPTL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL1658634 | 0.71 | ALDH1A1 (0.45) | LMNAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL12082358 | 0.70 | ALDH1A1 (0.44) | LMNAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL12082383 | 0.68 | MAPT (0.42) | LMNAMAPTMEN1KMT2APTGS2 | |
| SCHEMBL5590503 | 0.68 | LDHA (0.36) | MAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305633-B1 | Catechol derivative and its use | KISSEI PHARMACEUTICAL (JP) | 2013-03-20 | — | — | EP | claimed |