SCHEMBL1490893

SCHEMBL1490893

OB(O)c1ccc(F)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA3 P07451 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
ORAI1 Q96D31 1/20 0.37
ORAI2 Q96SN7 1/20 0.37
ORAI3 Q9BRQ5 1/20 0.37
TRPV6 Q9H1D0 1/20 0.37
ACHE P22303 1/20 0.36
ESR2 Q92731 1/20 0.34
NQO2 P16083 1/20 0.34
PTGS1 P23219 1/20 0.34
SPR P35270 1/20 0.34
DAO P14920 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
IDO1 P14902 1/20 0.33
DDO Q99489 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29722486 1.00 CA3 (0.52) CA3CA6CA5ACA9CA14
SCHEMBL319589 0.81 CA3 (0.46) CA3CA6CA5ACA9CA14
SCHEMBL7772653 0.81 CA3 (0.46) CA3CA6CA5ACA9CA14
SCHEMBL30586687 0.81 CA3 (0.46) CA3CA6CA5ACA9CA14
SCHEMBL39406 0.78 CES2 (0.43) CA3CA6CA5ACA9CA14
SCHEMBL29395656 0.78 CES2 (0.43) CA3CA6CA5ACA9CA14
SCHEMBL10269424 0.77 MAOA (0.40) ESR2PTGS1KDM4ENPC1
SCHEMBL408067 0.76 ACHE (0.41) CA3CA6CA5ACA9CA14
SCHEMBL29426963 0.76 ACHE (0.41) CA3CA6CA5ACA9CA14
SCHEMBL3791591 0.75 TYR (0.42) CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118515534-B Multi-tooth ligand, multi-tooth ligand metal catalyst, and preparation method and application thereof 华南理工大学 2024-11-05 CN claimed
CN-118515534-A Multi-tooth ligand, multi-tooth ligand metal catalyst, and preparation method and application thereof 华南理工大学 2024-08-20 CN claimed
CN-116731315-B Boron-containing phthalonitrile resin and preparation method and application thereof 中国科学院化学研究所 2024-06-21 CN claimed
CN-116731315-A Boron-containing phthalonitrile resin and preparation method and application thereof 中国科学院化学研究所 2023-09-12 CN claimed
CN-111146496-B Polymer electrolyte and lithium ion battery containing same 珠海冠宇电池股份有限公司 2021-07-13 CN claimed
CN-111146496-A Polymer electrolyte and lithium ion battery containing same 珠海冠宇电池有限公司 2020-05-12 CN claimed
EP-4213843-B1 MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS MERCK SHARP & DOHME LLC (US) 2026-05-06 EP disclosed
EP-4347571-B1 TRIAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER. HOFFMANN LA ROCHE (CH) 2026-04-22 EP disclosed
US-12599676-B2 Cytotoxic imidazo[1,2-A]pyridine compounds and their use in therapy MyricX Pharma Limited (GB) 2026-04-14 US disclosed
US-12590106-B2 Spiromacrocyclic orexin 2 receptor agonists H. LUNDBECK A/S (DK) 2026-03-31 US disclosed
US-12570650-B2 6-substituted pyridazine compounds as SMARCA2 and/or SMARCA4 degraders AURIGENE ONCOLOGY LIMITED (IN) 2026-03-10 US disclosed
US-12559491-B2 Modified imidazopyridines as glucosylceramide synthase inhibitors MERCK SHARP & DOHME LLC (US) 2026-02-24 US disclosed
US-20260048136-A1 CYTOTOXIC IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY MYRICX PHARMA LTD (GB) 2026-02-19 US disclosed
EP-1706403-A2 IMIDAZO[4,5-C]PYRIDINE COMPOUNDS AND METHODS OF ANTIVIRAL TREATMENT K.U.Leuven Research & Development (BE) 2006-10-04 EP disclosed
US-20060100262-A1 Tetracyclic indole derivatives as antiviral agents ISTITUTO DI RICHERCHEDI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IRMB) (IT) 2006-05-11 US disclosed
WO-2006046030-A2 TETRACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) 2006-05-04 WO disclosed
US-20050222198-A1 Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment K.U. LEUVEN RESEARCH & DEVELOPMENT, GERHARD PUERSTINGER AND GILEAD SCIENCES, INC. 2005-10-06 US disclosed
US-20050197338-A1 Substituted pyrazole urea compounds for the treatment of inflammation PHARMACIA AND UPJOHN COMPANY LLC 2005-09-08 US disclosed
WO-2005063744-A2 IMIDAZO[4,5-c]PYRIDINE COMPOUNDS AND METHODS OF ANTIVIRAL TREATMENT K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) 2005-07-14 WO disclosed
WO-2005037797-A1 SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION PHARMACIA CORPORATION (US) 2005-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559491-B2 Modified imidazopyridines as glucosylceramide synthase inhibitors GBA1, GBA2, GALC CA3 1721/4885CA6 716/4885CA5A 846/4885
US-20060100262-A1 Tetracyclic indole derivatives as antiviral agents IDO1, ZC3HAV1, IDO2 CA3 3112/4885CA6 2107/4885CA5A 1632/4885
US-20050197338-A1 Substituted pyrazole urea compounds for the treatment of inflammation IL4, ARG2, CASP4 CA3 3714/4885CA6 3810/4885CA5A 3072/4885
US-20260048136-A1 CYTOTOXIC IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY SLC7A1, FLT3, ABL1 CA3 3504/4885CA6 1485/4885CA5A 2260/4885
US-12590106-B2 Spiromacrocyclic orexin 2 receptor agonists HCRTR2, HCRTR1, OXER1 CA3 1783/4885CA6 2958/4885CA5A 1571/4885
US-12599676-B2 Cytotoxic imidazo[1,2-A]pyridine compounds and their use in therapy ABL1, FLT3, MTX2 CA3 3535/4885CA6 2350/4885CA5A 2677/4885
US-20050222198-A1 Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment CYP3A5, TPMT, TYMP CA3 3169/4885CA6 692/4885CA5A 249/4885
US-12570650-B2 6-substituted pyridazine compounds as SMARCA2 and/or SMARCA4 degraders SMARCC1, SMARCC2, SMARCA1 CA3 2530/4885CA6 206/4885CA5A 1059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.