SCHEMBL149503

SCHEMBL149503

CC1(C)c2ccc[c]c2-c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
MLNR O43193 1/20 0.38
NR1I2 O75469 1/20 0.38
CHRM2 P08172 1/20 0.38
ADRB1 P08588 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD2 P14416 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
CHRM3 P20309 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
OPRM1 P35372 1/20 0.38
DRD3 P35462 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2408845 0.85 HTR2A (0.33) HTR2APDK2PDK4
SCHEMBL23295734 0.84 CYP2D6 (0.30) CYP2D6
SCHEMBL2410642 0.82
SCHEMBL2409933 0.82
SCHEMBL2408147 0.82
SCHEMBL29070766 0.80 KMT2A (0.30) KMT2A
SCHEMBL28898829 0.79 PDK2 (0.36) HTR2AHTR2CPGRPDK2
SCHEMBL2413545 0.78 PGR (0.34) HTR2AMLNRNR1I2CHRM2ADRB1
SCHEMBL20554011 0.78 MMP2 (0.34)
SCHEMBL6293928 0.78 KDM4E (0.39) MEN1KMT2APDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107501244-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2022-05-03 CN claimed
CN-107556298-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-12-21 CN claimed
US-10418563-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-09-17 US claimed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO claimed
CN-107342368-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2019-05-28 CN claimed
EP-3211682-B1 AROMATIC HETEROCYCLIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE DEVICE MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO (JP) 2019-03-13 EP claimed
US-9893296-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-02-13 US claimed
CN-107556298-A Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2018-01-09 CN claimed
CN-107501244-A Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2017-12-22 CN claimed
US-9812661-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2017-11-07 US claimed
EP-3211682-A1 AROMATIC HETEROCYCLIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE DEVICE MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FIELD Idemitsu Kosan Co., Ltd (JP) 2017-08-30 EP claimed
US-20240239745-A1 METHOD FOR SYNTHESIZING BILIRUBIN Bilix Co., Ltd. (KR) 2024-07-18 US disclosed
US-20240237511-A1 PLURALITY OF ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-07-11 US disclosed
US-20240224794-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-07-04 US disclosed
US-20240208924-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-06-27 US disclosed
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-24 US disclosed
US-20100301318-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-12-02 US disclosed
US-20100301319-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-12-02 US disclosed
US-20100187511-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-07-29 US disclosed
EP-2159217-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240224794-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, L3MBTL4 HTR2A 4425/4885MLNR 3491/4885NR1I2 4559/4885
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE AOC1, EBPL, CYBA HTR2A 3050/4885MLNR 3490/4885NR1I2 3970/4885
US-10418563-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element RER1, L1CAM, ESR1 HTR2A 3598/4885MLNR 3500/4885NR1I2 266/4885
US-20240208924-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME VDAC2, CTCF, VDAC1 HTR2A 3630/4885MLNR 4415/4885NR1I2 4169/4885
US-20240237511-A1 PLURALITY OF ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, ODC1, PIEZO1 HTR2A 4707/4885MLNR 4555/4885NR1I2 3458/4885
US-20240239745-A1 METHOD FOR SYNTHESIZING BILIRUBIN CYP7A1, UGT1A3, UGT1A1 HTR2A 4323/4885MLNR 1461/4885NR1I2 561/4885
US-20100187511-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME TYR, DDC, OCIAD2 HTR2A 766/4885MLNR 3327/4885NR1I2 2968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.