SCHEMBL1497768

SCHEMBL1497768

O=C([O-])CCC(=O)OS(=O)(=O)O.[Na+]

nearest known ligand 0.37

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 3/20 0.34
CA4 known ✓ P22748 1/20 0.32
FFAR3 O14843 2/20 0.37
HDAC3 O15379 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
CASP1 P29466 1/20 0.31
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19993990 1.00 FFAR3 (0.37) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL27130887 1.00 FFAR3 (0.37) FFAR3HDAC3HDAC1HDAC2HDAC8
Sulfuric Acid SCHEMBL28848153 0.98 FFAR3 (0.36) FFAR3HDAC3HDAC1HDAC2HDAC8
Potassium Ion SCHEMBL10957419 0.95 FFAR3 (0.33) FFAR3HDAC3HDAC1HDAC2HDAC8
Butane SCHEMBL3658803 0.92 FFAR3 (0.46) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL362989 0.85 TSHR (0.38)
Biphenyl SCHEMBL3682453 0.84 LMNA (0.33)
SCHEMBL18130775 0.84
SCHEMBL2521502 0.83 TSHR (0.36)
Ammonia Solution, Strong SCHEMBL11776045 0.83 TSHR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240009120-A1 Ocular Compositions and Methods Thereof UNIVERSITY OF MISSISSIPPI MEDICAL CENTER 2024-01-11 US claimed
EP-4288026-A1 COMPOSITIONS COMPRISING A MULTI-TAIL SURFACTANT AND A CATIONIC POLYMER AND USES SPECIALTY OPERATIONS FRANCE (FR) 2023-12-13 EP claimed
WO-2022167672-A1 COMPOSITIONS COMPRISING A MULTI-TAIL SURFACTANT AND A CATIONIC POLYMER AND USES RHODIA OPERATIONS (FR) 2022-08-11 WO claimed
WO-2022150032-A1 SURFACTANT COMPOSITIONS WITH SUPRAMOLECULAR STRUCTURES FOR INDUSTRIAL, HOUSEHOLD, AGRICULTURAL AND OIL/GAS USE BPS JUST ENERGY TECHNOLOGY, LLC (US) 2022-07-14 WO claimed
EP-2794212-A1 PROCESS FOR THE MANUFACTURE OF A MESOPOROUS PRODUCT Saint-Gobain Centre de Recherches et d'Etudes Européen (FR) 2014-10-29 EP claimed
WO-2013093853-A1 PROCESS FOR THE MANUFACTURE OF A MESOPOROUS PRODUCT SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN (FR) 2013-06-27 WO claimed
WO-2009100441-A2 DEPOT FORMULATIONS IMPAX LABORATORIES, INC. (US) 2009-08-13 WO claimed
EP-1153051-A1 PROCESS FOR THE PREPARATION OF ANIONIC AQUEOUS POLYMER DISPERSIONS CONTAINING NO VOLATILE TERTIARY AMINE, OBTAINED DISPERSION AND COATING RESULTING FROM SAID DISPERSION STAHL INTERNATIONAL B.V. (NL) 2001-11-14 EP claimed
WO-2001027178-A1 PROCESS FOR THE PREPARATION OF ANIONIC AQUEOUS POLYMER DISPERSIONS CONTAINING NO VOLATILE TERTIARY AMINE, OBTAINED DISPERSION AND COATING RESULTING FROM SAID DISPERSION STAHL INTERNATIONAL B.V. (NL) 2001-04-19 WO claimed
EP-0009543-A1 Nested hollow fiber humidifier Jackson, Richard R., Dr. (US) 1980-04-16 EP claimed
US-3951877-A Heavy-duty granular detergent composition with sodium citrate builder LION FAT & OIL CO., LTD. (JA) 1976-04-20 US claimed
US-12622950-B2 Treatment of patients with severe von Willebrand disease undergoing elective surgery by administration of recombinant VWF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-12 US disclosed
US-12569435-B2 Ocular compositions and methods thereof UNIVERSITY OF MISSISSIPPI MEDICAL CENTER (US) 2026-03-10 US disclosed
EP-4637958-A1 HIGH PERFORMANCE FILTER MEDIA Hollingsworth & Vose Company (US) 2025-10-29 EP disclosed
EP-4583858-A1 COMBINATIONS COMPRISING PSYCHEDELICS FOR THE TREATMENT OF SCHIZOPHRENIA AND OTHER NEUROPSYCHIATRIC AND NEUROLOGIC DISORDERS Hadasit Medical Research Services&Development Ltd. (IL) 2025-07-16 EP disclosed
US-4249699-A FROM MINERAL MATTER OTISCA INDUSTRIES, LTD. (US) 1981-02-10 US disclosed
US-4244988-A Method of coating linear polyester with aqueous latex CIBA-GEIGY AG (CH) 1981-01-13 US disclosed
EP-0009543-A1 Nested hollow fiber humidifier Jackson, Richard R., Dr. (US) 1980-04-16 EP disclosed
EP-0008213-A1 The use of synthetic polymeric compositions as wallpaper adhesive Ciba Specialty Chemicals Water Treatments Limited (GB) 1980-02-20 EP disclosed
US-4160726-A Ultrafiltration process for the concentration of polymeric latices ABCOR, INC. (US) 1979-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569435-B2 Ocular compositions and methods thereof FLT1, VEGFA, AREG CA1 4858/4885CA4 4722/4885FFAR3 4513/4885
US-12622950-B2 Treatment of patients with severe von Willebrand disease undergoing elective surgery by administration of recombinant VWF F5, F8, F2 CA1 4681/4885CA4 4830/4885FFAR3 4800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.