Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12309185 | 0.81 | RBP4 (0.33) | RBP4 | |
| SCHEMBL2066202 | 0.74 | NPC1 (0.37) | RBP4TGFBR1SCN5A | |
| SCHEMBL446360 | 0.74 | PDE10A (0.38) | RBP4PDE10APDE4BPDE4APDE4C | |
| SCHEMBL2279044 | 0.73 | TGFBR1 (0.55) | RBP4TGFBR1PDE10ASCN5A | |
| SCHEMBL23414635 | 0.70 | ALPL (0.45) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29682918 | 0.70 | RBP4 (0.44) | RBP4PDE4BPDE4D | |
| SCHEMBL28947522 | 0.70 | RBP4 (0.37) | RBP4 | |
| SCHEMBL16972563 | 0.70 | PDE10A (0.42) | PDE10ASCN5A | |
| SCHEMBL12962511 | 0.70 | PDE10A (0.45) | RBP4PDE10ASCN5APTGS2 | |
| SCHEMBL1243656 | 0.70 | ALDH1A1 (0.45) | PDE10ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014072261-A1 | TRIAZOLO COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-05-15 | — | — | WO | claimed |
| JP-2011507902-A | — | — | 2011-03-10 | — | — | JP | claimed |
| EP-2235019-A1 | IMIDAZO [1,2-B] PYRIDAZINE COMPOUNDS AS MODULATORS OF LIVER X RECEPTORS | Wyeth LLC (US) | 2010-10-06 | — | — | EP | claimed |
| WO-2009086130-A1 | IMIDAZO [1,2-B] PYRIDAZINE COMPOUNDS AS MODULATORS OF LIVER X RECEPTORS | WYETH (US) | 2009-07-09 | — | — | WO | claimed |
| US-20250353841-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HUFF SARAH ELIZABETH (US) | 2025-11-20 | — | — | US | disclosed |
| CN-114133394-B | Compound selectively aiming at activity of cell cycle dependent kinase 12, preparation method and medical application | 赛诺哈勃药业（成都）有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114133394-A | Compound selectively aiming at activity of cell cycle dependent kinase 12, preparation method and medical application | 赛诺哈勃药业（成都）有限公司 | 2022-03-04 | — | — | CN | disclosed |
| US-11229208-B2 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-25 | — | — | US | disclosed |
| US-10939682-B2 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-03-09 | — | — | US | disclosed |
| US-20210037827-A1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-11 | — | — | US | disclosed |
| US-20160255837-A1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160255837-A1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, TST, SCLY | RBP4 3941/4885TGFBR1 2919/4885PDE10A 2398/4885 |
| US-20210037827-A1 | PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS | GSTA1, CYP1B1, DDT | RBP4 3110/4885TGFBR1 551/4885PDE10A 1205/4885 |
| US-20250353841-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HTT, HYPK, ATXN2 | RBP4 3943/4885TGFBR1 4817/4885PDE10A 2103/4885 |
| US-10939682-B2 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents | DDT, TST, SCLY | RBP4 3941/4885TGFBR1 2919/4885PDE10A 2398/4885 |
| US-11229208-B2 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents | GSTA1, CYP1B1, DDT | RBP4 3110/4885TGFBR1 551/4885PDE10A 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.