SCHEMBL1503969

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1504278	0.84	CA12 (0.50)	CA12CA1CA2CA9ALDH1A1
	SCHEMBL4947899	0.81	ALDH1A1 (0.48)	ALDH1A1LMNA
	SCHEMBL1504022	0.79	TDP1 (0.56)	ALDH1A1POLBMAPTNPC1RAB9A
	SCHEMBL1503971	0.78	ALDH1A1 (0.56)	CA12CA1CA2CA9ALDH1A1
	SCHEMBL4953267	0.74	SMN1; SMN2 (0.41)	ALDH1A1POLBMAPTRAB9AGAA
	SCHEMBL4621713	0.72	KMT2A (0.77)	CA12CA1CA2CA9ALDH1A1
	SCHEMBL12035862	0.71	MAPT (0.59)	CA12CA1CA2CA9ALDH1A1
	SCHEMBL16922181	0.70	NPC1 (0.66)	ALDH1A1KMT2AMEN1POLBMAPT
	SCHEMBL2098193	0.70	ALDH1A1 (0.59)	ALDH1A1KMT2AMEN1POLBMAPT
	SCHEMBL2098194	0.70	ALDH1A1 (0.59)	ALDH1A1KMT2AMEN1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.