SCHEMBL1503971

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1504279	0.84	KMT2A (0.55)	ALDH1A1MAPTGAAHPGDTSHR
	SCHEMBL12035862	0.84	MAPT (0.59)	ALDH1A1MAPTGAAHPGDALOX15
	SCHEMBL27784080	0.83	ALDH1A1 (0.58)	ALDH1A1MAPTGAAHPGDALOX15
	SCHEMBL3303537	0.81	ALDH1A1 (0.48)	ALDH1A1MAPTLMNA
	SCHEMBL1504023	0.79	RAB9A (0.56)	ALDH1A1GAATSHRNPC1RAB9A
	SCHEMBL1503969	0.78	CA12 (0.50)	ALDH1A1MAPTGAAHPGDALOX15
	SCHEMBL25205859	0.75	ALDH1A1 (0.65)	ALDH1A1MAPTGAAHPGDALOX15
	SCHEMBL3308530	0.74	TDP1 (0.44)	ALDH1A1MAPTGAAHPGDRAB9A
	SCHEMBL2098193	0.70	ALDH1A1 (0.59)	ALDH1A1MAPTGAAHPGDALOX15
	SCHEMBL16922181	0.70	NPC1 (0.66)	ALDH1A1MAPTGAAHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.