SCHEMBL15044501

SCHEMBL15044501

c1ccc(SSc2ccccn2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.77
EHMT1 Q9H9B1 1/20 0.77
APOBEC3G Q9HC16 1/20 0.77
HPGD P15428 4/20 0.55
MAPT P10636 4/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
HSD17B10 Q99714 2/20 0.55
MGLL Q99685 1/20 0.55
L3MBTL1 Q9Y468 3/20 0.47
ALDH1A1 P00352 4/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.39
USP2 O75604 1/20 0.39
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
POLB P06746 2/20 0.39
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11825400 0.93 EHMT2 (0.81) EHMT2EHMT1APOBEC3GHPGDMAPT
SCHEMBL21174 0.88 EHMT2 (1.00) EHMT2EHMT1APOBEC3GHPGDMAPT
SCHEMBL29349787 0.88 EHMT2 (1.00) EHMT2EHMT1APOBEC3GHPGDMAPT
SCHEMBL27972393 0.88 EHMT2 (1.00) EHMT2EHMT1APOBEC3GHPGDMAPT
SCHEMBL11824315 0.87 EHMT2 (0.71) EHMT2EHMT1APOBEC3GHPGDMAPT
Hydrochloric Acid SCHEMBL8671988 0.85 EHMT2 (0.94) EHMT2EHMT1APOBEC3GHPGDMAPT
Hydrochloric Acid SCHEMBL11726971 0.85 EHMT2 (0.94) EHMT2EHMT1APOBEC3GHPGDMAPT
Hydrochloric Acid SCHEMBL10707236 0.85 EHMT2 (0.94) EHMT2EHMT1APOBEC3GHPGDMAPT
Ammonia Solution, Strong SCHEMBL421495 0.85 EHMT2 (0.94) EHMT2EHMT1APOBEC3GHPGDMAPT
Hydrogen Sulfide SCHEMBL3347200 0.85 EHMT2 (0.94) EHMT2EHMT1APOBEC3GHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361260-A1 NUCLEOTIDE ANALOGUES SINGULAR GENOMICS SYSTEMS INC (US) 2025-11-27 US disclosed
US-12215122-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2025-02-04 US disclosed
US-20240400602-A1 NUCLEOTIDE ANALOGUES FIRST-CITIZENS BANK & TRUST COMPANY 2024-12-05 US disclosed
US-12145960-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2024-11-19 US disclosed
US-20240336711-A1 REAGENTS AND METHODS FOR ALIPHATIC CARBON-HYDROGEN BOND FUNCTIONALIZATION THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2024-10-10 US disclosed
US-20240316036-A1 DISULFIDE CONTAINING THERAPEUTICS AND DIAGNOSTICS FIRST-CITIZENS BANK & TRUST COMPANY 2024-09-26 US disclosed
US-20240269156-A1 DISULFIDE CONTAINING THERAPEUTICS FIRST-CITIZENS BANK & TRUST COMPANY 2024-08-15 US disclosed
US-20240174709-A1 NUCLEOTIDE ANALOGUES FIRST-CITIZENS BANK & TRUST COMPANY 2024-05-30 US disclosed
US-11958877-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2024-04-16 US disclosed
US-11878993-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2024-01-23 US disclosed
WO-2022241129-A1 REAGENTS AND METHODS FOR ALIPHATIC CARBON—HYDROGEN BOND FUNCTIONALIZATION THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2022-11-17 WO disclosed
WO-2022093800-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 WO disclosed
CN-113039191-A Nucleotide analogs 奇异基因组学系统公司 2021-06-25 CN disclosed
CN-110314238-A A kind of polypeptide drugs conjugate of cancer target and its preparation method and application 烟台药物研究所 2019-10-11 CN disclosed
CN-110314235-A A kind of reduction response type amphipathic stem antitumor medicine conjugate and its preparation method and application 烟台药物研究所 2019-10-11 CN disclosed
US-20180008543-A1 Cleavable Lipids RANA THERAPEUTICS, INC. 2018-01-11 US disclosed
US-9764036-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2017-09-19 US disclosed
US-9764036-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2017-09-19 US disclosed
US-20160213785-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2016-07-28 US disclosed
US-20160213785-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2016-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160213785-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS CETP, LCAT, NPC1L1 EHMT2 3480/4885EHMT1 3858/4885APOBEC3G 1504/4885
US-20240336711-A1 REAGENTS AND METHODS FOR ALIPHATIC CARBON-HYDROGEN BOND FUNCTIONALIZATION NCF1, SHROOM3, NPM1 EHMT2 286/4885EHMT1 367/4885APOBEC3G 1744/4885
US-12215122-B2 Nucleotide analogues NUDT1, POLN, TYMP EHMT2 2494/4885EHMT1 2450/4885APOBEC3G 226/4885
US-20240400602-A1 NUCLEOTIDE ANALOGUES ADAR, NUDT1, NSUN2 EHMT2 938/4885EHMT1 923/4885APOBEC3G 236/4885
US-20240316036-A1 DISULFIDE CONTAINING THERAPEUTICS AND DIAGNOSTICS GPX1, GPX4, PDIA4 EHMT2 2946/4885EHMT1 3031/4885APOBEC3G 4047/4885
US-20250361260-A1 NUCLEOTIDE ANALOGUES ADAR, NUDT1, NSUN2 EHMT2 938/4885EHMT1 923/4885APOBEC3G 236/4885
US-20180008543-A1 Cleavable Lipids PTDSS2, ACSS2, SARS1 EHMT2 3647/4885EHMT1 3920/4885APOBEC3G 2669/4885
US-20240269156-A1 DISULFIDE CONTAINING THERAPEUTICS P4HB, PDIA5, PDIA4 EHMT2 3151/4885EHMT1 3191/4885APOBEC3G 2768/4885
US-11958877-B2 Nucleotide analogues ITPA, POLB, NUDT1 EHMT2 2878/4885EHMT1 3389/4885APOBEC3G 437/4885
US-20240174709-A1 NUCLEOTIDE ANALOGUES NUDT1, POLN, TYMP EHMT2 2494/4885EHMT1 2450/4885APOBEC3G 226/4885
US-11878993-B2 Nucleotide analogues ITPA, POLB, NUDT1 EHMT2 2878/4885EHMT1 3389/4885APOBEC3G 437/4885
US-12145960-B2 Nucleotide analogues ITPA, POLB, NUDT1 EHMT2 2878/4885EHMT1 3389/4885APOBEC3G 437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.