SCHEMBL15046261

SCHEMBL15046261

Cc1nc(-c2cccnc2)nc(-c2cccnc2)n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.59
ALDH1A1 P00352 4/20 0.59
TP53 P04637 2/20 0.59
KDM4E B2RXH2 2/20 0.59
HPGD P15428 2/20 0.59
HSD17B10 Q99714 2/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
ALOX15 P16050 1/20 0.59
HTT P42858 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
CYP2A6 P11509 8/20 0.57
CYP3A4 P08684 5/20 0.56
CYP1A2 P05177 3/20 0.56
CHRNB2 P17787 1/20 0.52
CHRNA5 P30532 1/20 0.52
CHRNA4 P43681 1/20 0.52
TSHR P16473 3/20 0.51
NPSR1 Q6W5P4 2/20 0.51
NFKB1 P19838 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16606389 0.96 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1TP53KDM4EHPGD
SCHEMBL17779546 0.94 L3MBTL1 (0.70) SMN1; SMN2ALDH1A1TP53KDM4EHPGD
SCHEMBL18960595 0.93 L3MBTL1 (0.57) SMN1; SMN2ALDH1A1TP53KDM4EHPGD
SCHEMBL19164684 0.91 ALDH1A1 (0.60) SMN1; SMN2ALDH1A1TP53KDM4EHPGD
SCHEMBL19164686 0.91 L3MBTL1 (0.66) SMN1; SMN2ALDH1A1TP53KDM4EHPGD
SCHEMBL19164691 0.89 L3MBTL1 (0.53) SMN1; SMN2ALDH1A1TP53KDM4EHPGD
SCHEMBL29543568 0.89 SMN1; SMN2 (0.73) SMN1; SMN2ALDH1A1TP53KDM4EHPGD
SCHEMBL5032444 0.89 SMN1; SMN2 (0.73) SMN1; SMN2ALDH1A1TP53KDM4EHPGD
SCHEMBL21636465 0.87 L3MBTL1 (0.66) SMN1; SMN2ALDH1A1TP53KDM4EHPGD
SCHEMBL19164403 0.87 L3MBTL1 (0.66) SMN1; SMN2ALDH1A1TP53KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230380274-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-23 US disclosed
US-20230380274-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-23 US disclosed
US-11758808-B2 Ortho-substituted thermally activated delayed fluorescence material and organic light-emitting device comprising same SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-12 US disclosed
US-11758808-B2 Ortho-substituted thermally activated delayed fluorescence material and organic light-emitting device comprising same SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-12 US disclosed
US-20230189641-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20230189641-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-11569453-B2 Polycyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2023-01-31 US disclosed
WO-2021135181-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed
US-11031560-B2 Compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2021-06-08 US disclosed
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same LG CHEM, LTD. 2021-02-02 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180138422-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed
US-20180138422-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed
US-20180123049-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-03 US disclosed
US-20180123049-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-03 US disclosed
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
WO-2017061810-A1 DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2017-04-13 WO disclosed
US-9559312-B1 Imidazole compound, material for electronic device, electroluminescent device, and electronic device thereof E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2017-01-31 US disclosed
US-9559312-B1 Imidazole compound, material for electronic device, electroluminescent device, and electronic device thereof E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2017-01-31 US disclosed
WO-2013089460-A1 NOVEL CHEMICAL COMPOUND HAVING AN ACRIDINE STRUCTURE, AND ORGANIC LIGHT-EMITTING DIODE USING SAME 주식회사 두산 (KR) 2013-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same NR2E3, ALDH1A2, CRY1 SMN1; SMN2 3131/4885ALDH1A1 35/4885TP53 3727/4885
US-11031560-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 SMN1; SMN2 3052/4885ALDH1A1 1081/4885TP53 2214/4885
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 SMN1; SMN2 3766/4885ALDH1A1 87/4885TP53 4582/4885
US-20230189641-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME TEAD2, TEAD3, TEAD4 SMN1; SMN2 2282/4885ALDH1A1 884/4885TP53 886/4885
US-20230380274-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME TEAD2, TEAD3, TEAD4 SMN1; SMN2 2282/4885ALDH1A1 884/4885TP53 886/4885
US-20180123049-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME TEAD2, TEAD3, TEAD4 SMN1; SMN2 2282/4885ALDH1A1 884/4885TP53 886/4885
US-11758808-B2 Ortho-substituted thermally activated delayed fluorescence material and organic light-emitting device comprising same TEAD2, TEAD3, TEAD4 SMN1; SMN2 2282/4885ALDH1A1 884/4885TP53 886/4885
US-11569453-B2 Polycyclic compound and organic light emitting element comprising same PPOX, NFE2L2, OGFOD1 SMN1; SMN2 4116/4885ALDH1A1 830/4885TP53 3465/4885
US-20180138422-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ESR1, ETV6 SMN1; SMN2 3052/4885ALDH1A1 1081/4885TP53 2214/4885
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME NR2E3, CRY1, CRY2 SMN1; SMN2 2826/4885ALDH1A1 73/4885TP53 3438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.