Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847451 | 0.74 | GSK3A (0.46) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL2795967 | 0.69 | ALDH1A1 (0.54) | TSHRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15055132 | 0.69 | ALDH1A1 (0.47) | TSHRALDH1A1KMT2AMAPTPOLB | |
| SCHEMBL23009248 | 0.68 | KDM4E (0.63) | TSHRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15055948 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL2301820 | 0.66 | — | — | |
| SCHEMBL7553199 | 0.66 | ALDH1A1 (0.56) | TSHRALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL15055647 | 0.66 | KMT2A (0.47) | TSHRALDH1A1MEN1KMT2APOLB | |
| SCHEMBL16277156 | 0.66 | SIGMAR1 (0.50) | TSHRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11362739 | 0.65 | TSHR (0.59) | TSHRALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407383-B2 | Cyclopentene and cyclopentadiene compounds for controlling invertebrate pests | BASF SE (DE) | 2019-09-10 | — | — | US | disclosed |
| EP-3102563-B1 | CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2019-04-10 | — | — | EP | disclosed |
| EP-3013822-B1 | THIOPHENE- OR FURAN-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS AS PESTICIDES | MERIAL INC (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9732051-B2 | Isothiazoline compounds for combating invertebrate pests | BASF SE (DE) | 2017-08-15 | — | — | US | disclosed |
| EP-3102563-A1 | CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2016-12-14 | — | — | EP | disclosed |
| US-20160355466-A1 | CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2016-12-08 | — | — | US | disclosed |
| US-20160297808-A1 | Thiophene- or furan-substituted isothiazoline Compounds as Pesticides | MERIAL, INC. (US) | 2016-10-13 | — | — | US | disclosed |
| US-20160145223-A1 | Bicyclyl-Substituted Isothiazoline Compounds | BASF SE (DE) | 2016-05-26 | — | — | US | disclosed |
| EP-3013820-A1 | BICYCLYL-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS | BASF SE (DE) | 2016-05-04 | — | — | EP | disclosed |
| EP-3013822-A1 | THIOPHENE- OR FURAN-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS AS PESTICIDES | Merial, Inc. (US) | 2016-05-04 | — | — | EP | disclosed |
| WO-2015114157-A1 | CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2015-08-06 | — | — | WO | disclosed |
| WO-2014206910-A1 | BICYCLYL-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014206909-A1 | THIOPHENE- OR FURAN-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS AS PESTICIDES | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
| US-20140364466-A1 | Isothiazoline compounds for combating invertebrate pests | BASF SE (DE) | 2014-12-11 | — | — | US | disclosed |
| EP-2794601-A1 | ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013092943-A1 | ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145223-A1 | Bicyclyl-Substituted Isothiazoline Compounds | BROX, TUBA3C, SYMPK | TSHR 3743/4885ALDH1A1 2335/4885MEN1 2856/4885 |
| US-20160297808-A1 | Thiophene- or furan-substituted isothiazoline Compounds as Pesticides | PTMS, DDT, PIR | TSHR 814/4885ALDH1A1 1576/4885MEN1 2818/4885 |
| US-10407383-B2 | Cyclopentene and cyclopentadiene compounds for controlling invertebrate pests | PPIE, ECI1, PPID | TSHR 4726/4885ALDH1A1 667/4885MEN1 2944/4885 |
| US-20140364466-A1 | Isothiazoline compounds for combating invertebrate pests | PIR, ACHE, INMT | TSHR 2195/4885ALDH1A1 2079/4885MEN1 2387/4885 |
| US-20160355466-A1 | CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | PPIE, ECI1, PPID | TSHR 4726/4885ALDH1A1 667/4885MEN1 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.