Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.60 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | CLK3 | P49761 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150787 | 0.84 | BCAT2 (0.53) | RAB9ANPC1KCNK3MEN1KMT2A | |
| SCHEMBL28268366 | 0.78 | LMNA (0.61) | LMNAHIF1AROCK2ROCK1PIM1 | |
| SCHEMBL1571386 | 0.77 | LMNA (1.00) | LMNAHIF1AROCK2ROCK1PIM1 | |
| SCHEMBL153149 | 0.76 | LMNA (0.58) | LMNAHIF1AROCK2ROCK1PIM1 | |
| Nicotinanilide SCHEMBL352439 | 0.76 | LMNA (0.83) | LMNAHIF1AROCK2ROCK1PIM1 | |
| Nicotinanilide SCHEMBL29067673 | 0.76 | LMNA (0.83) | LMNAHIF1AROCK2ROCK1PIM1 | |
| SCHEMBL14880208 | 0.76 | ROCK2 (1.00) | LMNAHIF1AROCK2ROCK1PIM1 | |
| SCHEMBL11090153 | 0.75 | NAMPT (0.78) | LMNAHIF1AROCK2ROCK1RAB9A | |
| Nicotinanilide SCHEMBL8155304 | 0.74 | LMNA (0.81) | LMNAHIF1AROCK2ROCK1PIM1 | |
| SCHEMBL19520187 | 0.74 | LMNA (0.81) | LMNAHIF1AROCK2ROCK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841427-A2 | SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2015-03-04 | — | — | EP | claimed |
| WO-2013072528-A2 | SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2013-05-23 | — | — | WO | claimed |
| US-9512113-B2 | N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxylic thioamides and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2016-12-06 | — | — | US | disclosed |
| US-9398768-B2 | Substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)pyridin-3-yl-carboxamide compounds and their use as herbicides | BASF SE (DE) | 2016-07-26 | — | — | US | disclosed |
| US-9398768-B2 | Substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)pyridin-3-yl-carboxamide compounds and their use as herbicides | BASF SE (DE) | 2016-07-26 | — | — | US | disclosed |
| US-9398768-B2 | Substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)pyridin-3-yl-carboxamide compounds and their use as herbicides | BASF SE (DE) | 2016-07-26 | — | — | US | disclosed |
| US-9370184-B2 | 6-pyridone-2-carbamoyl-azoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2016-06-21 | — | — | US | disclosed |
| EP-2844650-B1 | 6-PYRIDON-2-CARBAMOYL-AZOLES AND THEIR APPLICATION AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2016-03-23 | — | — | EP | disclosed |
| EP-2855437-B1 | N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYL CARBOXYLIC ACID ATHIOAMIDES AND USE OF SAME AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2016-03-23 | — | — | EP | disclosed |
| US-20150175588-A1 | N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXYLIC THIOAMIDES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150119249-A1 | Substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)pyridin-3-yl-carboxamide compounds and their use as herbicides | BASF SE (DE) | 2015-04-30 | — | — | US | disclosed |
| EP-2841427-A2 | SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2015-03-04 | — | — | EP | disclosed |
| EP-2841427-A2 | SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2015-03-04 | — | — | EP | disclosed |
| WO-2014184017-A1 | SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2014-11-20 | — | — | WO | disclosed |
| WO-2014184017-A1 | SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2014-11-20 | — | — | WO | disclosed |
| WO-2013174843-A1 | N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXYLIC THIOAMIDES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013164333-A1 | 6-PYRIDONE-2-CARBAMOYL-AZOLES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2013-11-07 | — | — | WO | disclosed |
| WO-2013072528-A3 | SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2013-07-04 | — | — | WO | disclosed |
| WO-2013072528-A2 | SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072528-A2 | SUBSTITUTED N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175588-A1 | N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXYLIC THIOAMIDES AND USE THEREOF AS HERBICIDES | NAT1, TST, AADAC | LMNA 3507/4885HIF1A 2926/4885ROCK2 3433/4885 |
| US-20150119249-A1 | Substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)pyridin-3-yl-carboxamide compounds and their use as herbicides | NTRK3, CBR3, PDXK | LMNA 2815/4885HIF1A 3676/4885ROCK2 2528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.