Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 5/20 | 0.53 |
| ▸ | CA1 known ✓ | P00915 | 5/20 | 0.53 |
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.49 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15210455 | 0.88 | MAPT (0.54) | CA12CA1CA2CA9MAPT | |
| SCHEMBL15219449 | 0.85 | GRIK1 (0.60) | CA12CA1CA2CA9MAPT | |
| SCHEMBL15210370 | 0.84 | GRIK1 (0.59) | CA12CA1CA2CA9MAPT | |
| SCHEMBL21773340 | 0.82 | IDH1 (0.61) | CA12CA1CA2CA9TSHR | |
| SCHEMBL17255097 | 0.80 | RAD51 (0.61) | CA12CA1CA2CA9MAPT | |
| SCHEMBL29455562 | 0.80 | RAD51 (0.61) | CA12CA1CA2CA9MAPT | |
| SCHEMBL4057351 | 0.80 | RAD51 (0.61) | CA12CA1CA2CA9MAPT | |
| SCHEMBL15212535 | 0.77 | POLB (0.46) | CA12CA1CA2CA9MAPT | |
| SCHEMBL15219645 | 0.76 | KCNJ6 (0.55) | CA12CA1CA2CA9MAPT | |
| SCHEMBL15210456 | 0.75 | KCNJ6 (0.53) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817402-B1 | COLOR PROTECTION DETERGENT | HENKEL AG & CO KGAA (DE) | 2017-07-05 | — | — | EP | disclosed |
| US-8940681-B2 | Color protection detergent | HENKEL AG & CO. KGAA (DE) | 2015-01-27 | — | — | US | disclosed |
| EP-2817402-A1 | COLOR PROTECTION DETERGENT | Henkel AG&Co. KGAA (DE) | 2014-12-31 | — | — | EP | disclosed |
| US-20140352080-A1 | COLOR PROTECTION DETERGENT | HENKEL AG & CO. KGAA (DE) | 2014-12-04 | — | — | US | disclosed |
| WO-2013123981-A1 | COLOR PROTECTION DETERGENT | HENKEL AG & CO. KGAA (DE) | 2013-08-29 | — | — | WO | disclosed |