Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.50 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.50 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 6/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.50 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.50 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255097 | 1.00 | RAD51 (0.61) | RAD51ENPP2CA12CA1CA2 | |
| SCHEMBL29455562 | 1.00 | RAD51 (0.61) | RAD51ENPP2CA12CA1CA2 | |
| SCHEMBL9321648 | 0.86 | ENPP2 (0.74) | ENPP2CA12CA1CA2CA9 | |
| SCHEMBL14437899 | 0.86 | ENPP2 (0.74) | ENPP2CA12CA1CA2CA9 | |
| SCHEMBL31389389 | 0.85 | RAD51 (0.72) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL15282738 | 0.84 | ENPP2 (0.72) | ENPP2CA12CA1CA2CA9 | |
| SCHEMBL17255098 | 0.84 | ENPP2 (0.72) | ENPP2CA12CA1CA2CA9 | |
| SCHEMBL26977995 | 0.84 | ENPP2 (0.72) | ENPP2CA12CA1CA2CA9 | |
| SCHEMBL15210455 | 0.83 | MAPT (0.54) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL31389377 | 0.82 | RAD51 (0.70) | RAD51APEX1MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126375-A1 | MARKING COMPOSITION FOR APPLICATION ON A SPORTS PROJECTILE | GROUNDTOUCH GMBH (DE) | 2023-07-06 | — | — | WO | disclosed |
| EP-3030077-B1 | FORMULATIONS AND NANOPARTICLES OF SILICA WITH INSECT REPELLENT ACTIVITY ON TEXTILE SUBSTRATE AND OTHER MATERIALS AND RESPECTIVE PROCESS OF PREPARATION AND FIXATION | SUCCESS GADGET NANOTECNOLOGIA E NOVOS MATERIAIS LDA (PT) | 2019-09-11 | — | — | EP | disclosed |
| US-9810630-B1 | Fluorescent marking gel compositions and methods of use | ECOLAB USA INC. (US) | 2017-11-07 | — | — | US | disclosed |
| EP-3030077-A1 | COMPOUNDS AND REACTIVE NANOPARTICLES OP SILICA WITH INSECT REPELLENT ACTIVITY ON TEXTILE SUBSTRATE AND OTHER MATERIALS AND RESPECTIVE PROCESS OF PREPARATION AND BINDING | Ecoticket, Lda (PT) | 2016-06-15 | — | — | EP | disclosed |
| EP-2838577-A1 | HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES WITH VISUALIZATION MOIETY | SurModics, Inc. (US) | 2015-02-25 | — | — | EP | disclosed |
| US-8956682-B2 | Hydrophilic polymeric coatings for medical articles with visualization moiety | SURMODICS, INC. (US) | 2015-02-17 | — | — | US | disclosed |
| WO-2014200378-A1 | COMPOUNDS AND REACTIVE NANOPARTICLES OP SILICA WITH INSECT REPELLENT ACTIVITY ON TEXTILE SUBSTRATE AND OTHER MATERIALS AND RESPECTIVE PROCESS OF PREPARATION AND BINDING | ECOTICKET, LDA (PT) | 2014-12-18 | — | — | WO | disclosed |
| WO-2013151991-A1 | HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES WITH VISUALIZATION MOIETY | SURMODICS, INC. (US) | 2013-10-10 | — | — | WO | disclosed |
| US-20130261566-A1 | HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES WITH VISUALIZATION MOIETY | SURMODICS, INC. (US) | 2013-10-03 | — | — | US | disclosed |
| US-20090250183-A1 | PAPER COATING OR BINDING FORMULATIONS AND METHODS OF MAKING AND USING SAME | BASF SE (DE) | 2009-10-08 | — | — | US | disclosed |
| EP-1417360-B1 | METHOD FOR THE PRODUCTION OF FIBRES OR A FIBROUS PRODUCT IN AN ELECTROSTATIC SPINNING METHOD | HELSA AUTOMOTIVE GMBH & CO KG (DE) | 2004-12-22 | — | — | EP | disclosed |
| US-20040207126-A1 | Method for the production of fibres or a fibrous product in an electrostatic spinning method | HELSA-AUTOMOTIVE GMBH & CO. KG (DE) | 2004-10-21 | — | — | US | disclosed |
| EP-1417360-A1 | METHOD FOR THE PRODUCTION OF FIBRES OR A FIBROUS PRODUCT IN AN ELECTROSTATIC SPINNING METHOD | HELSA-WERKE HELMUT SANDLER GmbH & CO. KG (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003014430-A1 | METHOD FOR THE PRODUCTION OF FIBRES OR A FIBROUS PRODUCT IN AN ELECTROSTATIC SPINNING METHOD | HELSA-WERKE HELMUT SANDLER GMBH & CO. KG (DE) | 2003-02-20 | — | — | WO | disclosed |
| US-5879674-A | SIMPLE SELF-AGGLOMERATION OF COAL FINES HEATED TO AT LEAST 600 DEGREES CELCIUS FOR AT LEAST 5 MINUTES | AMERICAN CYANAMID COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| EP-0568731-A1 | Methods and compositions containing pesticides and stilbene compounds for enhanced pesticidal activity | AMERICAN CYANAMID COMPANY (US) | 1993-11-10 | — | — | EP | disclosed |
| US-5246936-A | Methods and compositions containing pesticides and stilbene compounds for enhanced pesticidal activity | AMERICAN CYANAMID COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5055195-A | Coagulation, filtration, separation form whole blood; having two strongly polar groups separated by aromatic or heteroaroma tic rings | BOEHRINGER MANNHEIM GMBH (DE) | 1991-10-08 | — | — | US | disclosed |
| EP-0163854-B1 | PROCESS FOR THE ELIMINATION OF FLUORESCENCE AND CATIONIC OR AMPHOTERIC AROMATIC NITRO COMPOUNDS | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0303894-A2 | Radiation sterilizable composition and articles made therefrom | AMERICAN CYANAMID COMPANY (US) | 1989-02-22 | — | — | EP | disclosed |