Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.50 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.50 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 6/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.50 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.50 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29455562 | 1.00 | RAD51 (0.61) | RAD51ENPP2CA12CA1CA2 | |
| SCHEMBL4057351 | 1.00 | RAD51 (0.61) | RAD51ENPP2CA12CA1CA2 | |
| SCHEMBL9321648 | 0.86 | ENPP2 (0.74) | ENPP2CA12CA1CA2CA9 | |
| SCHEMBL14437899 | 0.86 | ENPP2 (0.74) | ENPP2CA12CA1CA2CA9 | |
| SCHEMBL31389389 | 0.85 | RAD51 (0.72) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL15282738 | 0.84 | ENPP2 (0.72) | ENPP2CA12CA1CA2CA9 | |
| SCHEMBL17255098 | 0.84 | ENPP2 (0.72) | ENPP2CA12CA1CA2CA9 | |
| SCHEMBL26977995 | 0.84 | ENPP2 (0.72) | ENPP2CA12CA1CA2CA9 | |
| SCHEMBL15210455 | 0.83 | MAPT (0.54) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL31389377 | 0.82 | RAD51 (0.70) | RAD51APEX1MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002603-A1 | ACTIVE ENERGY RAY-CURABLE COMPOSITION WITH DARK PART CURABILITY | TOAGOSEI CO., LTD. (JP) | 2024-01-04 | — | — | US | disclosed |
| EP-2944477-B1 | MULTICOLOR THERMAL RECORDING MATERIAL, AND METHOD FOR COLOR FORMATION OF SAID MULTICOLOR THERMAL RECORDING MATERIAL | OJI HOLDINGS CORP (JP) | 2019-04-10 | — | — | EP | disclosed |
| US-9387714-B2 | Multicolor thermal recording material, and method for color formation of said multicolor thermal recording material | Oji Holdings Corporation (JP) | 2016-07-12 | — | — | US | disclosed |
| US-20150343825-A1 | MULTICOLOR THERMAL RECORDING MATERIAL, AND METHOD FOR COLOR FORMATION OF SAID MULTICOLOR THERMAL RECORDING MATERIAL | Oji Holdings Corporation (JP) | 2015-12-03 | — | — | US | disclosed |
| EP-2944477-A1 | MULTICOLOR THERMAL RECORDING MATERIAL, AND METHOD FOR COLOR FORMATION OF SAID MULTICOLOR THERMAL RECORDING MATERIAL | Oji Holdings Corporation (JP) | 2015-11-18 | — | — | EP | disclosed |