Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12074811 | 0.87 | PIM1 (0.39) | FAAHHRH3PIM1PIM3PIM2 | |
| SCHEMBL1120132 | 0.85 | GPR119 (0.47) | — | |
| SCHEMBL1120131 | 0.82 | HRH3 (0.33) | HRH3HSD11B1PIM1PIM3PIM2 | |
| SCHEMBL13616248 | 0.81 | PLAT (0.40) | PIM1PIM3PIM2 | |
| SCHEMBL2952296 | 0.81 | CASP8 (0.42) | FAAH | |
| Hydrochloric Acid SCHEMBL1120118 | 0.81 | PLAT (0.39) | PIM1PIM3PIM2 | |
| SCHEMBL1045160 | 0.80 | HTR2C (0.44) | FAAHHRH3TRPC3TRPC6 | |
| SCHEMBL1884146 | 0.80 | CASP3 (0.48) | FAAHPPARG | |
| SCHEMBL15313014 | 0.79 | PIM1 (0.37) | FAAHPIM1PIM3PIM2SMO | |
| SCHEMBL1120023 | 0.78 | ALDH1A1 (0.34) | FAAHPIM1PIM3PIM2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150237859-A1 | Thiazol-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-27 | — | — | US | disclosed |
| US-9029549-B2 | Thiazol-4-carboxylic acid esters and thioesters as plant protection agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-20140031553-A1 | Thiazol-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| US-8569509-B2 | Thiazole-4-carboxylic acid esters and thioesters as plant protection agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-29 | — | — | US | disclosed |
| US-8501781-B2 | Heteroarylpiperidine and -piperazine derivatives | BAYER CROPSCIENCE AG (DE) | 2013-08-06 | — | — | US | disclosed |
| CN-102712634-A | Heteroarylpiperidine and -piperazine derivatives | BAYER CROPSCIENCE AG | 2012-10-03 | — | — | CN | disclosed |
| US-20110306620-A1 | Heteroarylpiperidine And-Piperazine Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-12-15 | — | — | US | disclosed |
| US-20110105429-A1 | Thiazole-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306620-A1 | Heteroarylpiperidine And-Piperazine Derivatives | CAT, DPM1, ERG28 | FAAH 4031/4885HRH3 1758/4885HSD11B1 3100/4885 |
| US-20140031553-A1 | Thiazol-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | LYPLA1, ACOT7, PPT1 | FAAH 585/4885HRH3 1173/4885HSD11B1 870/4885 |
| US-20110105429-A1 | Thiazole-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | ACOT7, LYPLA1, PPT1 | FAAH 504/4885HRH3 1147/4885HSD11B1 1026/4885 |
| US-20150237859-A1 | Thiazol-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | LYPLA1, ACOT7, PPT1 | FAAH 585/4885HRH3 1173/4885HSD11B1 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.