Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344285 | 0.91 | NAMPT (0.49) | NAMPTHPGDPOLBHTTMCHR1 | |
| SCHEMBL12961110 | 0.91 | HTT (0.61) | NAMPTPOLBHTTMCHR1HDAC1 | |
| SCHEMBL15344403 | 0.88 | NAMPT (0.65) | NAMPTHPGDSIRT1SIRT2HDAC1 | |
| SCHEMBL16383171 | 0.85 | HTT (0.56) | NAMPTPOLBHTTMCHR1HDAC1 | |
| SCHEMBL14608288 | 0.85 | HTT (0.56) | NAMPTPOLBHTTMCHR1HDAC1 | |
| SCHEMBL16129581 | 0.84 | SIRT1 (0.59) | POLBHTTSIRT1SIRT2 | |
| SCHEMBL16383169 | 0.84 | NAMPT (0.60) | NAMPTHPGDHTT | |
| SCHEMBL14574172 | 0.84 | HTT (0.55) | NAMPTHPGDPOLBHTTMCHR1 | |
| SCHEMBL7513232 | 0.84 | FPR2 (0.57) | POLBHTTSIRT1SIRT2HDAC1 | |
| SCHEMBL7505669 | 0.84 | CNR1 (0.63) | POLBHTTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9084735-B2 | Self-assembling bis-urea compounds for drug delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-07-21 | — | — | US | disclosed |
| US-20150037390-A1 | SELF-ASSEMBLING BIS-UREA COMPOUNDS FOR DRUG DELIVERY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-02-05 | — | — | US | disclosed |
| US-8921426-B2 | Cationic bis-urea compounds as effective antimicrobial agents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130281515-A1 | CATIONIC BIS-UREA COMPOUNDS AS EFFECTIVE ANTIMICROBIAL AGENTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281515-A1 | CATIONIC BIS-UREA COMPOUNDS AS EFFECTIVE ANTIMICROBIAL AGENTS | NOS3, NOS1, NOS2 | NAMPT 3268/4885HPGD 3878/4885POLB 1098/4885 |
| US-20150037390-A1 | SELF-ASSEMBLING BIS-UREA COMPOUNDS FOR DRUG DELIVERY | SLC14A1, NONO, PUF60 | NAMPT 4199/4885HPGD 4210/4885POLB 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.