SCHEMBL154206

SCHEMBL154206

NC12CC3CC(C1)CC(N)(C3)C2(N)N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 4/20 0.47
GRIN3B O60391 4/20 0.47
GRIN1 Q05586 4/20 0.47
GRIN2A Q12879 4/20 0.47
GRIN2B Q13224 4/20 0.47
GRIN2C Q14957 4/20 0.47
GRIN3A Q8TCU5 4/20 0.47
LMNA P02545 2/20 0.47
SLC22A2 O15244 2/20 0.47
SLC47A1 Q96FL8 2/20 0.47
SLC22A1 O15245 1/20 0.47
TSHR P16473 1/20 0.47
NFKB1 P19838 1/20 0.47
STAT6 P42226 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
THRB P10828 2/20 0.45
POLB P06746 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL866125 0.86 GRIN2D (0.53) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24173315 0.73 PKM (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL4435547 0.69 GRIN2D (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6854205 0.69 GRIN2D (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1229980 0.69 GRIN2D (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Fluoride SCHEMBL22204318 0.68 GRIN2D (0.36) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Water SCHEMBL343274 0.68 GRIN2D (0.36) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL21445322 0.68 LMNA (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL28180581 0.68 LMNA (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6860339 0.67 LMNA (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11078581-B2 Catalyst composite and method for manufacturing the same UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2021-08-03 US claimed
CN-109046449-B Tertiary amine-thiourea bifunctional chiral catalyst and preparation method and application thereof 石家庄学院 2021-04-06 CN claimed
US-20200240026-A1 CATALYST COMPOSITE AND METHOD FOR MANUFACTURING THE SAME UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLGY) (KR) 2020-07-30 US claimed
US-9777320-B2 Molecular adaptors for dye conjugates PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2017-10-03 US claimed
US-20120058473-A1 Molecular Adaptors for Dye Conjugates PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-08 US claimed
US-20050085555-A1 Composition, synthesis and therapeutic applications of polyamines MURPHY, MICHAEL A. 2005-04-21 US claimed
US-20030013772-A1 Composition, synthesis and therapeutic applications of polyamines MURPHY, MICHAEL A. 2003-01-16 US claimed
CN-114276506-A Diamond type three-dimensional covalent organic framework material and preparation method thereof 江南大学 2022-04-05 CN disclosed
US-11078581-B2 Catalyst composite and method for manufacturing the same UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2021-08-03 US disclosed
CN-109046449-B Tertiary amine-thiourea bifunctional chiral catalyst and preparation method and application thereof 石家庄学院 2021-04-06 CN disclosed
CN-109046449-B Tertiary amine-thiourea bifunctional chiral catalyst and preparation method and application thereof 石家庄学院 2021-04-06 CN disclosed
US-20200240026-A1 CATALYST COMPOSITE AND METHOD FOR MANUFACTURING THE SAME UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLGY) (KR) 2020-07-30 US disclosed
US-7291919-B2 Interlayer dielectric film, and method for forming the same and interconnection MATSUSHITA ELECTRICAL INDUSTRIAL CO., LTD. (JP) 2007-11-06 US disclosed
US-6794528-B2 HEAT RESISTANCE, FLAME RETARDERS, STABILIZERS; REACTING DIALCOHOL COMPOUND WITH A PHOSPHYL OXYCHLORIDE COMPOUND DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-21 US disclosed
US-20030153719-A1 Novel polymer compound, precursor for the same and thin film-forming method using the same polymer precursor CHISSO CORPORATION (JP) 2003-08-14 US disclosed
US-20030109736-A1 Phosphorus compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-12 US disclosed
EP-1277758-A1 PHOSPHORUS COMPOUND Daicel Chemical Industries, Ltd. (JP) 2003-01-22 EP disclosed
US-20020034873-A1 Mechanical strength, thermal resistance, and adhesion to a substrate MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-03-21 US disclosed
US-4329522-A 1,3,5,7-Tetranitroadamantane and process for preparing same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1982-05-11 US disclosed
US-4284484-A REACTING ACETONITRILE WITH TETRAIODOADAMANTANE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1981-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030013772-A1 Composition, synthesis and therapeutic applications of polyamines TXN2, PYCR1, SQOR GRIN2D 263/4885GRIN3B 328/4885GRIN1 202/4885
US-20050085555-A1 Composition, synthesis and therapeutic applications of polyamines PRDX5, PINK1, ARG2 GRIN2D 2506/4885GRIN3B 1119/4885GRIN1 1466/4885
US-20120058473-A1 Molecular Adaptors for Dye Conjugates ALKBH1, ALKBH5, ALKBH3 GRIN2D 4560/4885GRIN3B 4267/4885GRIN1 4319/4885
US-20030109736-A1 Phosphorus compound NR4A1, POLL, NR0B1 GRIN2D 2300/4885GRIN3B 2801/4885GRIN1 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.