SCHEMBL15524645

SCHEMBL15524645

O=c1[nH]cnn1Cc1ccco1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
MEN1 O00255 3/20 0.47
POLB P06746 3/20 0.47
KMT2A Q03164 3/20 0.47
APEX1 P27695 2/20 0.47
RECQL P46063 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
HSD17B10 Q99714 2/20 0.47
PSMD14 O00487 1/20 0.47
MMP2 P08253 1/20 0.47
DNMT1 P26358 1/20 0.47
PTPN7 P35236 1/20 0.47
HBB P68871 1/20 0.47
KDM4C Q9H3R0 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TSHR P16473 3/20 0.44
KDM4E B2RXH2 2/20 0.43
USP2 O75604 1/20 0.43
THRB P10828 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11362739 0.70 TSHR (0.59) MAPTMEN1POLBKMT2AAPEX1
SCHEMBL5362573 0.68 KDM4E (0.51) MAPTMEN1POLBKMT2AAPEX1
SCHEMBL176271 0.65
SCHEMBL7553199 0.65 ALDH1A1 (0.56) MAPTPOLBL3MBTL1TSHRALDH1A1
SCHEMBL2795967 0.65 ALDH1A1 (0.54) MAPTMEN1POLBKMT2AAPEX1
SCHEMBL11699502 0.64 TSHR (0.58) MAPTMEN1POLBKMT2ATDP1
SCHEMBL2115613 0.64 MAPT (1.00) MAPTMEN1POLBKMT2AAPEX1
SCHEMBL23009248 0.63 KDM4E (0.63) MAPTMEN1POLBKMT2AAPEX1
SCHEMBL31267078 0.63 TSHR (0.50) MAPTMEN1POLBKMT2AAPEX1
SCHEMBL18462113 0.63 ADORA2B (0.48) MAPTMEN1KMT2AHSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170015638-A1 Use of N-(1,3,4-Oxadiazol-2-yl)arylcarboxamides or their salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to HPPD inhibitor herbicides BASF SE (DE) 2017-01-19 US disclosed
US-9101141-B2 N-(1,3,4-oxadiazol-2-yl)arylcarboxamides and use thereof as herbicides BAYER INTERLLECTUAL PROPERTY GMBH (DE) 2015-08-11 US disclosed
US-20140080705-A1 N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170015638-A1 Use of N-(1,3,4-Oxadiazol-2-yl)arylcarboxamides or their salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to HPPD inhibitor herbicides HPD, AADAC, PGD MAPT 4442/4885MEN1 4807/4885POLB 360/4885
US-20140080705-A1 N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES PRDX4, CBR3, AOX1 MAPT 4744/4885MEN1 4775/4885POLB 2507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.