SCHEMBL15801366

SCHEMBL15801366

CC(C)(C)c1ccc(N(c2ccc(C(C)(C)C)cc2)C(C)(C)C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
LMNA P02545 1/20 0.46
TYR P14679 1/20 0.46
KIF11 P52732 2/20 0.39
ALDH1A1 P00352 5/20 0.38
HSD17B10 Q99714 2/20 0.37
HPGD P15428 2/20 0.37
NPC1 O15118 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 1/20 0.37
HDAC1 Q13547 1/20 0.37
SLC22A2 O15244 1/20 0.37
SLC22A1 O15245 1/20 0.37
SLC22A3 O75751 1/20 0.37
KCNH2 Q12809 1/20 0.36
BCHE P06276 3/20 0.36
ACHE P22303 3/20 0.36
ALOX15 P16050 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20059986 0.91 RAB9A (0.45) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL24206102 0.85 KIF11 (0.46) TSHRKIF11RAB9A
SCHEMBL20059981 0.85 TSHR (0.58) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL24206207 0.85 NR1H2 (0.41) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL18352212 0.85 KIF11 (0.46) TSHRKIF11RAB9A
SCHEMBL24206428 0.82 ALDH1A1 (0.44) TSHRLMNATYRALDH1A1HSD17B10
SCHEMBL24206382 0.82 NR1H2 (0.47) TSHRLMNATYRKIF11NPC1
SCHEMBL24206219 0.81 MEN1 (0.37) LMNAALDH1A1RAB9AKCNH2ACHE
SCHEMBL24206427 0.81 ALDH1A1 (0.43) TSHRLMNAALDH1A1HSD17B10HPGD
SCHEMBL24206223 0.81 TSHR (0.42) TSHRLMNATYRALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11778895-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11778895-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11765965-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-11765965-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
WO-2023142485-A1 BORON-NITROGEN COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 季华恒烨(佛山)电子材料有限公司 2023-08-03 WO disclosed
US-20230225205-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-13 US disclosed
US-20230225205-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-13 US disclosed
US-20230141820-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed
US-20230141820-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed
US-20230014761-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-19 US disclosed
US-20210257557-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-08-19 US disclosed
US-20210234099-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-07-29 US disclosed
WO-2021135750-A1 ORGANIC COMPOUND, APPLICATION THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed
US-20210135111-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-05-06 US disclosed
US-20210074934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 US disclosed
US-20210066598-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-04 US disclosed
US-20210066616-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-04 US disclosed
US-20200058885-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM, LTD. (KR) 2020-02-20 US disclosed
US-8993130-B2 Organic compound and organic electroluminescent device using the same Yen, Feng-wen (TW) 2015-03-31 US disclosed
US-20140166988-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2014-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210074934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 TSHR 4153/4885LMNA 2197/4885TYR 619/4885
US-20230014761-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 TSHR 4275/4885LMNA 1767/4885TYR 503/4885
US-20210257557-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OTC, OSBPL3 TSHR 4494/4885LMNA 2129/4885TYR 771/4885
US-11765965-B2 Organic electroluminescent materials and devices YBX3, YBX1, LEF1 TSHR 601/4885LMNA 606/4885TYR 409/4885
US-20210066598-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 TSHR 4153/4885LMNA 2197/4885TYR 619/4885
US-20210135111-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES YBX3, YBX1, LEF1 TSHR 601/4885LMNA 606/4885TYR 409/4885
US-20210234099-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EPCAM, PIEZO1, OR10J3 TSHR 4202/4885LMNA 1630/4885TYR 87/4885
US-20230141820-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME TPH1, HTR1D, ECE1 TSHR 1596/4885LMNA 833/4885TYR 1241/4885
US-20200058885-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME TMEM109, CRY1, TRPA1 TSHR 4828/4885LMNA 3037/4885TYR 486/4885
US-20230225205-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP TSHR 4235/4885LMNA 2012/4885TYR 298/4885
US-20210066616-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP TSHR 4235/4885LMNA 2012/4885TYR 298/4885
US-11778895-B2 Organic electroluminescent materials and devices EPCAM, PIEZO1, OR10J3 TSHR 4202/4885LMNA 1630/4885TYR 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.