SCHEMBL15852154

SCHEMBL15852154

Cc1cccc(N(c2ccc(-c3ccccc3)cc2)c2cc3c4cc(N(c5ccc(-c6ccccc6)cc5)c5cccc(C)c5)c5ccccc5c4oc3c3ccccc23)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B1 P14061 1/20 0.36
▸ HSD17B2 P37059 1/20 0.36
▸ NPC1 O15118 3/20 0.35
▸ RAB9A P51151 3/20 0.35
▸ HPGD P15428 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ TSHR P16473 1/20 0.35
▸ EPHX1 P07099 2/20 0.34
▸ POLB P06746 3/20 0.33
▸ MAPT P10636 2/20 0.33
▸ TP53 P04637 2/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ CTDSP1 Q9GZU7 1/20 0.32
▸ CYP1A1 P04798 2/20 0.32
▸ CYP1A2 P05177 2/20 0.32
▸ CYP1B1 Q16678 2/20 0.32
▸ SIGMAR1 Q99720 1/20 0.31
▸ TNKS O95271 2/20 0.31
▸ NR1I3 Q14994 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15852152 0.94 HSD17B1 (0.36) HSD17B1HSD17B2NPC1RAB9AHPGD
SCHEMBL15852138 0.93 SIGMAR1 (0.34) NPC1RAB9AHPGDSMN1; SMN2TSHR
SCHEMBL22381219 0.93 CYP1A1 (0.35) HSD17B1HSD17B2NPC1RAB9AHPGD
SCHEMBL24859907 0.91 CA12 (0.33) HSD17B1HSD17B2NPC1RAB9AHPGD
SCHEMBL15852142 0.91 MAPT (0.34) HSD17B1HSD17B2NPC1RAB9AHPGD
SCHEMBL15852143 0.91 MAPT (0.34) HSD17B1HSD17B2NPC1RAB9AHPGD
SCHEMBL15852145 0.91 SIGMAR1 (0.35) NPC1RAB9AHPGDSMN1; SMN2TSHR
SCHEMBL15852147 0.90 CYP1A1 (0.34) NPC1RAB9AHPGDSMN1; SMN2TSHR
SCHEMBL15852161 0.89 PLA2G2A (0.35) MAPTCYP1A1CYP1A2CYP1B1TNKS
SCHEMBL15852149 0.89 MAOB (0.38) NPC1RAB9AHPGDSMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839138-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-12-05 — — US disclosed
US-20230047477-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 — — US disclosed
US-20230042023-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-09 — — US disclosed
US-20230019712-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-19 — — US disclosed
US-20230011996-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2023-01-12 — — US disclosed
US-20220285625-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-09-08 — — US disclosed
US-20220169656-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO., LTD. (JP) 2022-06-02 — — US disclosed
US-20220029099-A1 NOVEL COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-01-27 — — US disclosed
US-10777752-B2 Organic electroluminescence device and electronic apparatus provided with the same IDEMITSU KOSAN CO., LTD. (JP) 2020-09-15 — — US disclosed
US-10763441-B2 Organic electroluminescence device and electronic apparatus provided with the same IDEMITSU KOSAN CO., LTD. (JP) 2020-09-01 — — US disclosed
US-20200111973-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-04-09 — — US disclosed
US-20200111962-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-04-09 — — US disclosed
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-23 — — US disclosed
US-20170324043-A1 OXYGEN-CONTAINING FUSED RING AMINE COMPOUND, SULFUR-CONTAINING FUSED RING AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-11-09 — — US disclosed
US-20170324043-A1 OXYGEN-CONTAINING FUSED RING AMINE COMPOUND, SULFUR-CONTAINING FUSED RING AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-11-09 — — US disclosed
US-9755156-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2017-09-05 — — US disclosed
US-9755156-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2017-09-05 — — US disclosed
US-20140183500-A1 ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-07-03 — — US disclosed
US-20140183500-A1 ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230011996-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME RER1, RPS19, ESR1 HSD17B1 2155/4885HSD17B2 2096/4885NPC1 2777/4885
US-20200111973-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME RER1, RPS19, MRPS22 HSD17B1 2726/4885HSD17B2 1819/4885NPC1 3659/4885
US-20220169656-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS RPS19, TERT, PIEZO1 HSD17B1 3372/4885HSD17B2 2919/4885NPC1 2643/4885
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device AOC2, SQOR, AOC1 HSD17B1 3033/4885HSD17B2 2264/4885NPC1 4655/4885
US-10777752-B2 Organic electroluminescence device and electronic apparatus provided with the same RER1, RPS19, MRPS22 HSD17B1 2726/4885HSD17B2 1819/4885NPC1 3659/4885
US-20170324043-A1 OXYGEN-CONTAINING FUSED RING AMINE COMPOUND, SULFUR-CONTAINING FUSED RING AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE AOC2, SQOR, AOC1 HSD17B1 3033/4885HSD17B2 2264/4885NPC1 4655/4885
US-20220029099-A1 NOVEL COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME RER1, RIF1, RPS19 HSD17B1 1615/4885HSD17B2 1326/4885NPC1 3032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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