SCHEMBL159193

SCHEMBL159193

NC1(CC(=O)O)C=Cc2ccccc2C1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 6/20 0.36
MME P08473 1/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
PKM P14618 1/20 0.32
KMT2A Q03164 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27328867 0.79 HSD11B1 (0.36) HSD11B1MMEPKMKMT2AMAOA
SCHEMBL4679449 0.78 HSD11B1 (0.36) HSD11B1MMECYP3A4CYP2D6
SCHEMBL11741518 0.78 HSD11B1 (0.36) HSD11B1MMEPKMKMT2AMAOA
SCHEMBL28699182 0.77 NPSR1 (0.36) CYP3A4CYP2D6KMT2AMAOAMAOB
SCHEMBL4734678 0.76 MAOA (0.33) KMT2AMAOAMAOBHDAC9
SCHEMBL6059687 0.75 HSD11B1 (0.33) HSD11B1MMECYP3A4CYP2D6
SCHEMBL8068895 0.71 MAOA (0.35) MMEMAOAMAOBHDAC9
SCHEMBL4240413 0.71 MME (0.42) HSD11B1MMEPKMKMT2AMAOA
SCHEMBL8351271 0.71 PARP1 (0.34)
SCHEMBL7529245 0.70 CA1 (0.35) MMEMAOAMAOBHDAC9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240360177-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES AIMMAX THERAPEUTICS, INC. 2024-10-31 US claimed
EP-4396196-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES Aimmax Therapeutics, Inc. (US) 2024-07-10 EP claimed
CN-117897394-A Peptides with antimicrobial activity 美商安满药物开发公司 2024-04-16 CN claimed
WO-2023034481-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES AIMMAX THERAPEUTICS, INC. (US) 2023-03-09 WO claimed
US-8486370-B2 Heterocyclic ligands for integrin imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-07-16 US claimed
US-20100310455-A1 Heterocyclic Ligands for Integrin Imaging and Therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-12-09 US claimed
US-7576175-B2 Amino acid terminated diphenylurea derivatives; display high binding affinity, specificity, and stability; use in treating cancer, inflammatory diseases, and autoimmune diseases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-08-18 US claimed
WO-2008031016-A2 HETEROCYCLIC LIGANDS FOR INTEGRIN IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-13 WO claimed
WO-2005122379-A9 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY UNIV CALIFORNIA (US) 2006-03-09 WO claimed
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 US claimed
WO-2005122379-A2 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-22 WO claimed
WO-2026105061-A1 ANTIBODY-DRUG CONJUGATES THAT BIND CDCP1 AND USES THEREOF PHEON THERAPEUTICS LTD (GB) 2026-05-21 WO disclosed
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US disclosed
WO-2026090584-A2 METHODS OF TREATING PERIPHERAL NERVOUS SYSTEM MYELINATION CONDITIONS Artery Therapeutics, Inc. (US) 2026-04-30 WO disclosed
EP-4731270-A1 COMBINATION THERAPY WITH PEPTIDE RECEPTOR RADIONUCLIDE AND DNA REPAIR INHIBITOR The Regents of The University of California (US) 2026-04-29 EP disclosed
WO-2005122379-A9 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY UNIV CALIFORNIA (US) 2006-03-09 WO disclosed
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 US disclosed
WO-2005122379-A2 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-22 WO disclosed
US-20050256056-A1 Peptide inhibitors of HIV THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER UNIVERSITY OF CALIFORNIA (US) 2005-11-17 US disclosed
WO-2005056577-A2 PEPTIDE INHIBITORS OF HIV THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100310455-A1 Heterocyclic Ligands for Integrin Imaging and Therapy ITGA1, ITGAL, ITGA4 HSD11B1 4748/4885MME 2336/4885CYP3A4 4027/4885
US-20050256056-A1 Peptide inhibitors of HIV VIP, NGLY1, PEPD HSD11B1 4119/4885MME 45/4885CYP3A4 4142/4885
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy ITGA4, ITGB4, ITGA1 HSD11B1 4295/4885MME 2120/4885CYP3A4 3827/4885
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN GLP1R, ALB, GIPR HSD11B1 3842/4885MME 2784/4885CYP3A4 3997/4885
US-20240360177-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES VIP, FPR2, FPR1 HSD11B1 4121/4885MME 568/4885CYP3A4 3799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.