Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 8/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
| ▸ | BCKDK | O14874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27029227 | 0.82 | GPR35 (0.44) | GPR35PTPN1TSHRDAOBCKDK | |
| SCHEMBL23531561 | 0.78 | GPR35 (0.43) | GPR35PTPN1TSHRGSK3BBCKDK | |
| SCHEMBL21858819 | 0.78 | GPR35 (0.39) | GPR35PTPN1TSHRDAOBCKDK | |
| SCHEMBL4582179 | 0.78 | GPR35 (0.54) | GPR35PTPN1TSHRGSK3BDAO | |
| Hydrochloric Acid SCHEMBL8935194 | 0.76 | GPR35 (0.52) | GPR35PTPN1TSHRGSK3BDAO | |
| SCHEMBL1329709 | 0.75 | MAPT (0.48) | GPR35PTPN1TSHR | |
| SCHEMBL18701625 | 0.75 | DAO (0.39) | GPR35PTPN1TSHRDAOBCKDK | |
| SCHEMBL476351 | 0.74 | GPR35 (0.67) | GPR35PTPN1TSHRGSK3BDAO | |
| SCHEMBL23531554 | 0.74 | PTPN1 (0.41) | GPR35PTPN1TSHRDAO | |
| SCHEMBL21612058 | 0.73 | GPR35 (0.48) | GPR35PTPN1TSHRGSK3BDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884643-B2 | Substituted thiophenecarboxamides and analogues as antibacterials agents | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-30 | — | — | US | claimed |
| EP-3818050-B1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | BAYER AG (DE) | 2023-05-31 | — | — | EP | claimed |
| US-20230159506-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-25 | — | — | US | claimed |
| EP-3818050-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | Bayer Aktiengesellschaft (DE) | 2021-05-12 | — | — | EP | claimed |
| CN-112638893-A | Substituted thiophenecarboxamides and analogs as antibacterial agents | 拜耳公司 | 2021-04-09 | — | — | CN | claimed |
| WO-2020007905-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-09 | — | — | WO | claimed |
| US-12492196-B2 | Thienyloxazolones and analogues | BAYER AKTIENGESELLSCHAFT (DE) | 2025-12-09 | — | — | US | disclosed |
| CN-118496197-A | Substituted thiophenecarboxamides, thiophenecarboxylic acids and derivatives thereof | 拜耳公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-3994130-B1 | SUBSTITUTED THIOPHENE CARBOXAMIDES AND DERIVATIVES THEREOF AS MICROBICIDES | BAYER AG (DE) | 2024-07-10 | — | — | EP | disclosed |
| CN-114364663-B | Substituted thiophenecarboxamides and derivatives thereof as microbiocides | 拜耳公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-4077317-B1 | THIENYLOXAZOLONES AND ANALOGUES | BAYER AG (DE) | 2024-06-26 | — | — | EP | disclosed |
| CN-112638893-B | Substituted thiophenecarboxamides and analogues as antibacterial agents | 拜耳公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11884643-B2 | Substituted thiophenecarboxamides and analogues as antibacterials agents | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-30 | — | — | US | disclosed |
| WO-2020007905-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-09 | — | — | WO | disclosed |
| EP-2970228-B1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-8871783-B2 | Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (cyano-methyl)-amides inhibitors of cathepsin C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-28 | — | — | US | disclosed |
| US-8871783-B2 | Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (cyano-methyl)-amides inhibitors of cathepsin C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-28 | — | — | US | disclosed |
| WO-2014140078-A1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-18 | — | — | WO | disclosed |
| US-20140275114-A1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| US-20140275114-A1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275114-A1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | CTSC, CTSB, CTSV | GPR35 1917/4885PTPN1 2307/4885TSHR 4531/4885 |
| US-11884643-B2 | Substituted thiophenecarboxamides and analogues as antibacterials agents | XDH, TST, BLVRB | GPR35 3838/4885PTPN1 1169/4885TSHR 1736/4885 |
| US-12492196-B2 | Thienyloxazolones and analogues | PGLS, TH, TPI1 | GPR35 3995/4885PTPN1 1005/4885TSHR 2870/4885 |
| US-20230159506-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | XDH, TST, BLVRB | GPR35 3838/4885PTPN1 1169/4885TSHR 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.